<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1729-519X</journal-id>
<journal-title><![CDATA[Revista Habanera de Ciencias Médicas]]></journal-title>
<abbrev-journal-title><![CDATA[Rev haban cienc méd]]></abbrev-journal-title>
<issn>1729-519X</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Ciencias Médicas de la Habana]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1729-519X2020000700004</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Efecto hepatoprotector, antioxidante y anticancerígeno de la espirulina]]></article-title>
<article-title xml:lang="en"><![CDATA[Hepatoprotective, antioxidant and anticancer effect of Spirulina]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[García-Ishimine]]></surname>
<given-names><![CDATA[Richard]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rodríguez-Vega]]></surname>
<given-names><![CDATA[Juan]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Mejía-Pinedo]]></surname>
<given-names><![CDATA[Davis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Alas Peruanas Escuela de Farmacia y Bioquímica ]]></institution>
<addr-line><![CDATA[Lima ]]></addr-line>
<country>Peru</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad de Chiclayo Colegio San José de Chiclayo ]]></institution>
<addr-line><![CDATA[Lima ]]></addr-line>
<country>Peru</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<volume>19</volume>
<numero>6</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1729-519X2020000700004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1729-519X2020000700004&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1729-519X2020000700004&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  la espirulina es un alga que se emplea como un suplemento alimenticio de gran importancia, consumido desde la antigüedad, actualmente son conocidas sus propiedades como hepatoprotector, antioxidante, anticancerígeno, entre otros, que brindan una mejor salud y por ende calidad de vida. Actualmente las enfermedades hepáticas y el cáncer tienen prevalencia convirtiéndose en un gran problema sanitario que aqueja a la humanidad. En este sentido el presente trabajo halla su importancia.  Objetivo:  realizar una revisión sobre la actividad farmacológica de las diferentes especies de espirulina relacionadas con el efecto hepatoprotector, antioxidante y anticancerígeno.  Material y Métodos:  se implementó una búsqueda exhaustiva en base de datos en línea como Pubmed, Scopus, Medline y Ebsco, se incluyeron solo trabajos originales completos de corte experimental y clínico publicados en el periodo 2000 a 2019.  Desarrollo:  se encontraron 2064 artículos relacionados de los cuales 58 cumplían los requisitos exigidos en el presente trabajo, fueron trabajados por análisis documental y agrupación en clusters atendiendo a sus propiedades farmacognósicas.  Conclusiones:  los artículos revisados refieren el gran potencial que tiene la espirulina como agente hepatoprotector, antiinflamatorio, antioxidante, citotóxico, antimutagénico, apoptótico y anticancerígeno soportado en su gran variedad de contenido nutracéutico.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  Spirulina is an alga used as a food supplement of great importance that has been consumed since ancient times. At present, its hepatoprotective potential, antioxidant activity and anticancer effect among other properties are known. These properties provide better health and thus better quality of life. Currently, liver diseases and cancer have a significant prevalence, becoming a major health problem afflicting humankind. In this regard, the present work is particularly important.  Objective:  To review the pharmacological activity of different Spirulina species related to the hepatoprotective, antioxidant and anticancer effect.  Material and methods:  A rigorous search was carried out in online databases such as Pubmed, Scopus, Medline and EBSCO. Only complete original experimental and clinical works published from 2000 to 2019 were included.  Development:  A total of 2064 related articles were found. Of them, 58 fulfilled the requirements of the present work. Document analysis and cluster grouping were carried out taking into account its pharmacological properties.  Conclusions:  The reviewed articles provide information about the great potential of Spirulina as a hepatoprotective, anti-inflammatory, antioxidant, cytotoxic, antimutagenic, apoptotic and anticancer agent supported in its great variety of nutraceutical content.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[espirulina]]></kwd>
<kwd lng="es"><![CDATA[hepatoprotector]]></kwd>
<kwd lng="es"><![CDATA[cáncer]]></kwd>
<kwd lng="es"><![CDATA[antioxidante]]></kwd>
<kwd lng="es"><![CDATA[radicales libres]]></kwd>
<kwd lng="es"><![CDATA[anticancerígeno]]></kwd>
<kwd lng="en"><![CDATA[Spirulina]]></kwd>
<kwd lng="en"><![CDATA[hepatoprotective]]></kwd>
<kwd lng="en"><![CDATA[cancer]]></kwd>
<kwd lng="en"><![CDATA[antioxidant]]></kwd>
<kwd lng="en"><![CDATA[free radicals]]></kwd>
<kwd lng="en"><![CDATA[anticancer]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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