<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1729-519X</journal-id>
<journal-title><![CDATA[Revista Habanera de Ciencias Médicas]]></journal-title>
<abbrev-journal-title><![CDATA[Rev haban cienc méd]]></abbrev-journal-title>
<issn>1729-519X</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Ciencias Médicas de la Habana]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1729-519X2020000700011</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Lidocaína 2 % con adrenalina 1:80000 alcalinizada con bicarbonato de sodio 8,4 % en la anestesia dental]]></article-title>
<article-title xml:lang="en"><![CDATA[Lidocaine 2% with adrenaline 1: 80,000 alkalinized with sodium bicarbonate 8.4 % in dental anesthesia]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Chumpitaz-Cerrate]]></surname>
<given-names><![CDATA[Victor]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Caldas-Cueva]]></surname>
<given-names><![CDATA[Victoria]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Franco-Quino]]></surname>
<given-names><![CDATA[César Ivanovish]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Chávez-Rimache]]></surname>
<given-names><![CDATA[Lesly Karem]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Científica del Sur  ]]></institution>
<addr-line><![CDATA[Lima ]]></addr-line>
<country>Peru</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Nacional Mayor de San Marcos Facultad de Odontología ]]></institution>
<addr-line><![CDATA[Lima ]]></addr-line>
<country>Peru</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad Peruana Cayetano Heredia Escuela de Salud Pública y Administración ]]></institution>
<addr-line><![CDATA[Lima ]]></addr-line>
<country>Peru</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<volume>19</volume>
<numero>6</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1729-519X2020000700011&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1729-519X2020000700011&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1729-519X2020000700011&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción: La alcalinización de la lidocaína ha resultado ser exitosa en el bloqueo del nervio dentario inferior, sin embargo, existen resultados contradictorios respecto a su eficacia clínica.  Objetivo: Determinar el efecto de la lidocaína 2 % con adrenalina 1:80000 alcalinizada con bicarbonato de sodio al 8,4 % sobre el bloqueo del nervio dentario inferior.  Material y métodos: Estudio experimental, prospectivo y longitudinal conformado por 50 pacientes de la Facultad de Odontología de la Universidad Nacional Mayor de San Marcos. Las siguientes soluciones fueron administradas para el bloqueo del nervio dentario inferior: lidocaína 2 % con adrenalina 1:80000 alcalinizada con bicarbonato de sodio al 8,4 % y lidocaína 2 % con adrenalina 1:80000 no alcalinizada. Se evaluó la intensidad del dolor por la inyección, parámetros hemodinámicos y periodos anestésicos (tiempo de inicio de acción y duración del efecto anestésico).  Resultados: Se evidenció una menor intensidad del dolor por la inyección en el grupo de lidocaína alcalinizada (19,16 ± 2,7) en comparación al grupo de lidocaína no alcalinizada (22,88 ± 4,2); p=0,02. Así mismo, el tiempo de inicio de acción fue menor en el grupo de lidocaína alcalinizada (105,72 ± 9,7s) en comparación con el grupo de lidocaína no alcalinizada (157,52 ± 12,1); p=0,002. Sin embargo, no se evidenciaron diferencias significativas en los parámetros hemodinámicos (p&gt;0,05) y la duración del efecto anestésico (p=0,114).  Conclusiones: La lidocaína 2 % con adrenalina 1:80000 alcalinizada con bicarbonato de sodio al 8,4 % sobre el bloqueo del nervio dentario inferior produce una disminución de la intensidad del dolor por la inyección y del tiempo de inicio de acción, en comparación con la formulación no alcalinizada. Sin embargo, no se evidencian diferencias en relación con los parámetros hemodinámicos ni a la duración del efecto anestésico.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction: The alkalinization of lidocaine has been successful in blocking the inferior dental nerve; however, there are contradictory results regarding its clinical efficacy.  Objective: To determine the effect of 2% lidocaine with 1: 80,000 adrenaline alkalinized with 8.4% sodium bicarbonate on inferior dental nerve block.  Material and methods: Experimental, prospective and longitudinal study that comprised 50 patients from the Dental School of the National University of San Marcos. The following solutions were administered for inferior dental nerve block: 2% lidocaine with epinephrine 1: 80,000 alkalinized with 8.4% sodium bicarbonate and 2% lidocaine with 1: 80,000 adrenaline not alkalinized. Pain intensity was evaluated by injection, hemodynamic parameters and anesthetic periods (time of onset of action and duration of the anesthetic effect).  Results: There was a lower pain intensity due to injection in the alkalized lidocaine group (19.16 ± 2.7) compared to the non-alkalinized lidocaine group (22.88 ± 4.2); p=0.02. Likewise, the onset time of action was lower in the alkalized lidocaine group (105.72 ± 9.7) compared to the non-alkalinized lidocaine group (157.52 ± 12.1); p=0.002. However, no significant differences were found in the hemodynamic parameters (p&gt;0.05) and the duration of the anesthetic effect (p=0.114).  Conclusions: Lidocaine 2% with adrenaline 1: 80,000 alkalized with sodium bicarbonate at 8.4% on the block of the inferior dental nerve produces a decrease in pain intensity due to injection and the time of onset of action, compared to the non-alkalinized formulation. However, there are no differences in relation to the hemodynamic parameters or the duration of the anesthetic effect.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Anestésicos locales]]></kwd>
<kwd lng="es"><![CDATA[Lidocaína]]></kwd>
<kwd lng="es"><![CDATA[Alcalinización]]></kwd>
<kwd lng="es"><![CDATA[Bicarbonato de Sodio]]></kwd>
<kwd lng="es"><![CDATA[Signos Vitales]]></kwd>
<kwd lng="es"><![CDATA[Dolor]]></kwd>
<kwd lng="en"><![CDATA[Anesthetics]]></kwd>
<kwd lng="en"><![CDATA[local]]></kwd>
<kwd lng="en"><![CDATA[Lidocaine]]></kwd>
<kwd lng="en"><![CDATA[alkalinization]]></kwd>
<kwd lng="en"><![CDATA[Sodium Bicarbonate]]></kwd>
<kwd lng="en"><![CDATA[vital signs]]></kwd>
<kwd lng="en"><![CDATA[pain]]></kwd>
</kwd-group>
</article-meta>
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