<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2221-2434</journal-id>
<journal-title><![CDATA[Revista Finlay]]></journal-title>
<abbrev-journal-title><![CDATA[Rev. Finlay]]></abbrev-journal-title>
<issn>2221-2434</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Ciencias Médicas de Cienfuegos. Centro Provincial de información de Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2221-24342022000200208</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Una mirada al cáncer desde la perspectiva molecular]]></article-title>
<article-title xml:lang="en"><![CDATA[A Look at Cancer from a Molecular Perspective]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez Bouza]]></surname>
<given-names><![CDATA[María de Jesús]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez Frenes]]></surname>
<given-names><![CDATA[Pedro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Ayala Reina]]></surname>
<given-names><![CDATA[Zuria Elisa]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Sánchez Sánchez]]></surname>
<given-names><![CDATA[Pedro Javier]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Santos Solís]]></surname>
<given-names><![CDATA[Maylé]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas de Cienfuegos  ]]></institution>
<addr-line><![CDATA[Cienfuegos ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Banco de Sangre Provincial  ]]></institution>
<addr-line><![CDATA[Cienfuegos ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital General Universitario Dr. Gustavo Aldereguía Lima  ]]></institution>
<addr-line><![CDATA[Cienfuegos ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2022</year>
</pub-date>
<volume>12</volume>
<numero>2</numero>
<fpage>208</fpage>
<lpage>220</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S2221-24342022000200208&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S2221-24342022000200208&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S2221-24342022000200208&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[  RESUMEN  El cáncer es una enfermedad multifactorial que provoca alteraciones en la diferenciación celular y un descontrol en la proliferación normal de las células, lo que conlleva a una pérdida de las características estructurales y funcionales de las células en un tejido. Esta enfermedad constituye un importante problema de salud por sus consecuencias desde el punto de vista individual, social y económico. Se conoce que las alteraciones moleculares, tienen un importante rol en las bases fisiopatológicas del cáncer. Esto ha intensificado en los últimos años las investigaciones básicas biomédicas en ese campo como vía para conseguir una mejor prevención, diagnóstico y tratamiento de estas patologías. En la presente revisión se expone una actualización sobre algunos aspectos relacionados con las bases moleculares del cáncer, la cual puede brindar herramientas teóricas útiles para la acción en diferentes escenarios de las ciencias biológicas, médicas y de la salud que mejoren la esperanza de vida del paciente con un padecimiento oncológico.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Cancer is a multifactorial disease that causes alterations in cell differentiation and a lack of control in the normal proliferation of cells, which leads to a loss of the structural and functional characteristics of cells in a tissue. This disease constitutes an important health problem due to its consequences from the individual, social and economic point of view. Molecular alterations are known to play an important role in the pathophysiological basis of cancer. This has intensified basic biomedical research in this field in recent years as a way to achieve better prevention, diagnosis and treatment of these pathologies. This review presents an update on some aspects related to the molecular bases of cancer, which can provide useful theoretical tools for action in different scenarios of biological, medical and health sciences that improve the patient's life expectancy with an oncological condition.]]></p></abstract>
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<kwd lng="es"><![CDATA[neoplasias]]></kwd>
<kwd lng="es"><![CDATA[biología molecular]]></kwd>
<kwd lng="en"><![CDATA[neoplasms]]></kwd>
<kwd lng="en"><![CDATA[molecular biology]]></kwd>
</kwd-group>
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