<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2223-4861</journal-id>
<journal-title><![CDATA[Centro Azúcar]]></journal-title>
<abbrev-journal-title><![CDATA[cen. az.]]></abbrev-journal-title>
<issn>2223-4861</issn>
<publisher>
<publisher-name><![CDATA[Editorial Feijóo]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2223-48612023000200015</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[METODOLOGÍA PARA EL CÁLCULO DEL IMPACTO AMBIENTAL DE LA LOGÍSTICA FARMACÉUTICA EN CUBA]]></article-title>
<article-title xml:lang="en"><![CDATA[METHODOLOGY FOR ENVIRONMENTAL IMPACT CALCULATION OF PHARMACEUTICAL LOGISTICS IN CUBA]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Hernández Rech]]></surname>
<given-names><![CDATA[José Andrés]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Rosa Domínguez]]></surname>
<given-names><![CDATA[Elena R.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Abreu Ledón]]></surname>
<given-names><![CDATA[René]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Knudsen González]]></surname>
<given-names><![CDATA[José Alberto]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Central &#8220;Marta Abreu&#8221; de Las Villas Departamento de Ingeniería Industrial Facultad de Ingeniería Mecánica e Industrial]]></institution>
<addr-line><![CDATA[Santa Clara Villa Clara]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Universidad Central &#8220;Marta Abreu&#8221; de Las Villas Departamento de Ingeniería Química Facultad de Química y Farmacia]]></institution>
<addr-line><![CDATA[Santa Clara Villa Clara]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>06</month>
<year>2023</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>06</month>
<year>2023</year>
</pub-date>
<volume>50</volume>
<numero>2</numero>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S2223-48612023000200015&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S2223-48612023000200015&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S2223-48612023000200015&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción: El aumento del impacto ambiental en la logística farmacéutica, ha despertado el interés por el uso de herramientas como el Análisis de Ciclo de Vida (ACV) para lograr operaciones menos agresivas con el medioambiente. A pesar de esto, su uso continua siendo fragmentario y existe poca evidencia de su aplicación en la logística de medicamentos en Cuba. Por lo tanto, es necesario diseñar una herramienta para el apoyo a la toma de decisiones con enfoque en el impacto ambiental de las operaciones logísticas.  Objetivo:  Diseñar una metodología para el cálculo del impacto ambiental de las operaciones logísticas en la cadena de suministro de medicamentos en Cuba.  Materiales y Métodos:  A partir de la revisión de la literatura especializada, se diseñó una metodología con enfoque en el ACV y para el cálculo del impacto ambiental de la logística farmacéutica en Cuba. Además, se caracterizó el funcionamiento logístico de la cadena de suministro de medicamentos para contextualizar la aplicación de la metodología y favorecer la toma de decisiones.  Resultados y Discusión: Se diseñó una metodología adaptada a las características de la logística farmacéutica en Cuba. Esta constituye una guía para tomar decisiones enfocadas en las operaciones logísticas sostenibles. El diseño se llevó a cabo con enfoque en la mejora continua y la retroalimentación para asegurar la implementación efectiva.  Conclusiones: La aplicación de la metodología permitirá el diseño de los procesos logísticos a lo largo de la cadena de suministro de medicamentos para la selección de alternativas más limpias.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  The increasing environmental impact of pharmaceutical logistics has sparked interest in the use of tools such as Life Cycle Assessment (LCA) to achieve less environmentally aggressive operations. Despite this, its use remains fragmentary and there is little evidence of its application in the logistics of medicines in Cuba. Therefore, it is necessary to design a tool to support decision-making with a focus on the environmental impact of logistics operations.  Objective:  To design a tool to support decision-making with a focus on the environmental impact of logistics operations.  Materials and Methods: Based on a review of the specialised literature, a methodology was designed with a focus on LCA and for calculating the environmental impact of pharmaceutical logistics in Cuba. In addition, the logistical functioning of the pharmaceutical supply chain was characterised in order to contextualise the application of the methodology and facilitate decision-making.  Results and Discussion: A methodology adapted to the characteristics of pharmaceutical logistics in Cuba was designed. It constitutes a guideline for decision making focused on sustainable logistics operations. The design is carried out with a focus on continuous improvement and feedback to ensure effective implementation.  Conclusions: The application of the methodology will enable the design of logistics processes along the medicines supply chain for the selection of cleaner alternatives.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[análisis de ciclo de vida]]></kwd>
<kwd lng="es"><![CDATA[cadena de suministro]]></kwd>
<kwd lng="es"><![CDATA[farmacéutica]]></kwd>
<kwd lng="es"><![CDATA[impacto ambiental]]></kwd>
<kwd lng="es"><![CDATA[logística sostenible.]]></kwd>
<kwd lng="en"><![CDATA[life cycle assessment]]></kwd>
<kwd lng="en"><![CDATA[supply chain]]></kwd>
<kwd lng="en"><![CDATA[pharmaceutical]]></kwd>
<kwd lng="en"><![CDATA[environmental impact]]></kwd>
<kwd lng="en"><![CDATA[sustainable logistics.]]></kwd>
</kwd-group>
</article-meta>
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