<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2224-5421</journal-id>
<journal-title><![CDATA[Revista Cubana de Química]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Cub Quim]]></abbrev-journal-title>
<issn>2224-5421</issn>
<publisher>
<publisher-name><![CDATA[Ediciones UO, Universidad de Oriente]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2224-54212019000400058</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Biomateriales: del laboratorio al mercado]]></article-title>
<article-title xml:lang="en"><![CDATA[Biomaterials: from laboratory to market]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Wong-Hernández]]></surname>
<given-names><![CDATA[Lissy]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Bringas]]></surname>
<given-names><![CDATA[Ricardo]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Menendez]]></surname>
<given-names><![CDATA[Tamara]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Delgado]]></surname>
<given-names><![CDATA[José A.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Almirall]]></surname>
<given-names><![CDATA[Amisel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Alfonso]]></surname>
<given-names><![CDATA[Adrián]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Marrero]]></surname>
<given-names><![CDATA[Grisel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Zaldívar-Silva]]></surname>
<given-names><![CDATA[Dionisio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de La Habana Centro de Biomateriales ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Asociación Cubana de Comunicadores Sociales  ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af3">
<institution><![CDATA[,Universidad de La Habana Facultad de Química ]]></institution>
<addr-line><![CDATA[La Habana ]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2019</year>
</pub-date>
<volume>31</volume>
<fpage>58</fpage>
<lpage>70</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S2224-54212019000400058&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S2224-54212019000400058&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S2224-54212019000400058&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN Los biomateriales son componentes fundamentales de una rama en expansión de la industria médico-farmacéutica que incluye, entre otros, materiales de reparación y restauración de tejidos, y sistemas de liberación de fármacos y de diagnóstico in vitro. El Centro de Biomateriales de la Universidad de La Habana ha obtenido productos biomateriales como el adhesivo tisular Tisuacryl®; Multilatex®, soporte sólido para la elaboración de reactivos para el diagnóstico; y Biograft-G®, para rellenar cavidades en defectos óseos maxilofaciales. En el presente trabajo se revisan los principales resultados obtenidos con esos productos, con énfasis en las estrategias de comercialización. Como herramienta promocional se diseñó una imagen con un color distintivo que se incluyó en los materiales impresos como la literatura técnica, el plegable comercial, las etiquetas del envase primario y el envase secundario. Se imprimieron gigantografías con resultados de la aplicación de esos biomateriales para exhibiciones en ferias comerciales, reuniones y congresos científicos.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Biomaterials are key components of an expanding branch in the medical-pharmaceutical industry that manufacture restoratives and reparative tissue materials, drug delivery systems and in vitro diagnostics. The Center of Biomaterials of the University of Havana has developed several biomaterial products: the tissue adhesive Tisuacryl®; Multilatex®, a solid support for the development of diagnostic reagents; and Biograft-G®, a bone filling material used in maxillofacial surgery. In the present work, the main results achieved for these products are reviewed, with emphasis in the commercialization strategy. As a promotion tool, attractive and modern images with a distinctive color were designed and included in all printed material accompanying the products, including the technical literature, the commercial brochure, the label of primary packaging and secondary packaging. Giant posters including results of the application of these biomaterials were printed for each product to be exhibited in commercial fairs and scientific meeting and congresses.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[biomateriales]]></kwd>
<kwd lng="es"><![CDATA[mercado de biomateriales]]></kwd>
<kwd lng="es"><![CDATA[imagen]]></kwd>
<kwd lng="es"><![CDATA[literatura técnica]]></kwd>
<kwd lng="en"><![CDATA[biomaterials]]></kwd>
<kwd lng="en"><![CDATA[biomaterials market]]></kwd>
<kwd lng="en"><![CDATA[image]]></kwd>
<kwd lng="en"><![CDATA[technical literature]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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