<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2224-6185</journal-id>
<journal-title><![CDATA[Tecnología Química]]></journal-title>
<abbrev-journal-title><![CDATA[RTQ]]></abbrev-journal-title>
<issn>2224-6185</issn>
<publisher>
<publisher-name><![CDATA[Universidad de Oriente]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2224-61852019000100037</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Extracción y determinación del contenido de fructanos del tipo inulina del yacón (Smallanthus sonchifolius): esquema tecnológico para su producción industrial]]></article-title>
<article-title xml:lang="en"><![CDATA[Extraction and determination of inulin type fructan from yacón (Smallanthus sonchifolius): technological scheme for its industrial production]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Álvarez-Borroto]]></surname>
<given-names><![CDATA[Reynerio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[González-Gavilánez]]></surname>
<given-names><![CDATA[Humberto R.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Montenegro-Cepeda]]></surname>
<given-names><![CDATA[Andrea C.]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Central del Ecuador Facultad de Ingeniería Química ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Ecuador</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>04</month>
<year>2019</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>04</month>
<year>2019</year>
</pub-date>
<volume>39</volume>
<numero>1</numero>
<fpage>37</fpage>
<lpage>48</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S2224-61852019000100037&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S2224-61852019000100037&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S2224-61852019000100037&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN Se determinó el contenido de fructano del tipo inulina del Yacón (Smallanthus Sonchifolius), mediante un procedimiento estandarizado por Cromatografía Líquida de Alto Rendimiento (HPLC). Se empleó un diseño multifactorial 2&#94;3 usando el programa Statgraphics V. 16. Se seleccionaron tres variables independientes a dos niveles- temperatura: 333 K y 353 K; tiempo: 5 y 25 min; y una relación agua-yacón de 3 mL/200 g y 7 mL/200 g. El rendimiento máximo obtenido fue de 18%. Las condiciones óptimas de extracción fueron tiempo: 24 min, temperatura: 352 K, y la relación volumen de agua-masa de yacón fue de: 6,9 mL/200 g. Con el uso del programa SuperPro Designer se diseñó la tecnología de producción industrial mediante un proceso por lote. Se realizó el análisis económico a partir de una planta de 100 kg/día de procesamiento de materia prima y se obtuvo un Valor Actual Neto (VAN) de 200 005, una Tasa Interna de Retorno (TIR) de 40% y un tiempo de recuperación de la inversión de 19 meses. Los productos de la fermentación en el colon de fructanos del tipo inulina actúan como sustratos y señalizadores de moléculas en la regulación de la respuesta inmune, la homeostasis de la glucosa y el metabolismo de los lípidos, reduciendo los riesgos de hiperglucemia, obesidad y el cáncer colorrectal.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Content of inulin type fructan by mean a standardized procedure and using High Performance Liquid Chromatography (HPLC) was determined. A multifactorial design 2&#94;3 by using Statgraphics V. 16 software was employed. Three independent variables at two levels-temperature: 333 K y 353 K; time: 5 and 25 min, and water yacon ratio of 3 mL/200 g and 7 mL/200 g were selected. The maximum yield was of 18%. The optimal conditions for extracting were, time: 24 min; temperature: 352 K; and water volume-yacon mass ratio was 6,9 mL/200 g. By using SuperPro Designer software the industrial-production technology was designed for a batch process. For a 100 kg per day-processing plant of raw materials an economic analysis was performed, and net present value (NPV) of 200 005, an Internal Rate Return (ITR) of 40%, and a payback period of 19 months were obtained. The fermentation products of inulin type fructan at the colon act as subtracts and signaling of molecules in the regulation of immune response, the glucose homeostasis, and lipid metabolism, reducing the hyperglycemia, obesity, and colorectal cancer risks.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Yacón (Smallanthus sonchifolius)]]></kwd>
<kwd lng="es"><![CDATA[inulina]]></kwd>
<kwd lng="es"><![CDATA[tecnología]]></kwd>
<kwd lng="es"><![CDATA[HPLC]]></kwd>
<kwd lng="es"><![CDATA[extracción]]></kwd>
<kwd lng="en"><![CDATA[Yacon (Smallanthus sonchifolius)]]></kwd>
<kwd lng="en"><![CDATA[inulin]]></kwd>
<kwd lng="en"><![CDATA[technology]]></kwd>
<kwd lng="en"><![CDATA[HPLC]]></kwd>
<kwd lng="en"><![CDATA[extraction]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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