<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2227-1899</journal-id>
<journal-title><![CDATA[Revista Cubana de Ciencias Informáticas]]></journal-title>
<abbrev-journal-title><![CDATA[Rev cuba cienc informat]]></abbrev-journal-title>
<issn>2227-1899</issn>
<publisher>
<publisher-name><![CDATA[Editorial Ediciones Futuro]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2227-18992020000400162</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Comportamiento de la albúmina en pacientes pediátricos en estadíos de la sepsis]]></article-title>
<article-title xml:lang="en"><![CDATA[Behaviour of the albumin in pediatric patients in the stages of sepsis]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Navarro Céspedes]]></surname>
<given-names><![CDATA[Juan Manuel]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Álvarez González]]></surname>
<given-names><![CDATA[Idalis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Martell Betancourt]]></surname>
<given-names><![CDATA[Nelson Lázaro]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad Central &#8220;Marta Abreu&#8221; de las Villas  ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Pediátrico José Luis Miranda Unidad de cuidados intensivos ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<aff id="Af3">
<institution><![CDATA[,Hospital Pediátrico José Luis Miranda Unidad de cuidados intensivos ]]></institution>
<addr-line><![CDATA[ ]]></addr-line>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>12</month>
<year>2020</year>
</pub-date>
<volume>14</volume>
<numero>4</numero>
<fpage>162</fpage>
<lpage>173</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S2227-18992020000400162&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S2227-18992020000400162&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S2227-18992020000400162&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN Las proteínas constituyen uno de los elementos estructurales más importantes del organismo, dentro de ellos la albúmina es la más abundante y se considera imprescindible para el transporte de diversas sustancias así como para mantener el equilibrio hídrico tisular. Esto motivó a realizar un estudio sobre cómo afectan sus niveles sanguíneos a la salud humana. El presente trabajo tiene como objetivo determinar el comportamiento de la albúmina y su influencia en la evolución de pacientes pediátricos en diferentes estadíos de la sepsis. Para ello se elaboró una base de casos con los pacientes pediátricos en diferentes estadíos de sepsis en la cual se recogen todas las variables de interés para el estudio incluida el nivel de albúmina. Se realizó análisis estadístico utilizando tablas de contingencia, V de Cramer, técnicas de Inteligencia Artificial, entre otros; para obtener los resultados. Se muestra que la hipoalbuminemia constituye un factor que incrementa la mortalidad por shock séptico en los pacientes pediátricos, más aún si se asocia a comorbilidades como las enfermedades oncohematológicas. Los niveles de albúmina pueden influir en la evolución de los pacientes pediátricos con sepsis y podrían convertirse en un predictor de mortalidad.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT The proteins constitute one of the most important structural elements of the organism, within them the albumin is the most abundant and it is considered essential for the transport of diverse substances as well as to maintain the water hydric balance. This prompted a study on how their blood levels affect human health. The goal of this paper is to determine the behavior of albumin and its influence on the evolution of pediatric patients in different stages of sepsis. For it a database was elaborated with pediatric patients in different stages of sepsis in which all the variables of interest for the study, including the albumin level, were collected. Statistical analysis was carried out using contingency tables, V de Cramer, Artificial Intelligence techniques, among others; to get the results. Hypoalbuminemia as a factor that increases mortality due to septic shock in pediatric patients, even more so if it is associated with comorbidities such as oncohematological diseases was showed. The Albumin levels can influence the evolution of pediatric patients with sepsis and could become a predictor of mortality.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[nivel de albúmina]]></kwd>
<kwd lng="es"><![CDATA[estadío de la sepsis]]></kwd>
<kwd lng="es"><![CDATA[comorbilidades]]></kwd>
<kwd lng="es"><![CDATA[estado al egreso]]></kwd>
<kwd lng="es"><![CDATA[tablas de contingencia]]></kwd>
<kwd lng="en"><![CDATA[albumin level]]></kwd>
<kwd lng="en"><![CDATA[stage of sepsis]]></kwd>
<kwd lng="en"><![CDATA[comorbidities]]></kwd>
<kwd lng="en"><![CDATA[status at discharge]]></kwd>
<kwd lng="en"><![CDATA[contingency tables]]></kwd>
</kwd-group>
</article-meta>
</front><back>
<ref-list>
<ref id="B1">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Delaney]]></surname>
<given-names><![CDATA[A. P]]></given-names>
</name>
<name>
<surname><![CDATA[Dan]]></surname>
<given-names><![CDATA[A]]></given-names>
</name>
<name>
<surname><![CDATA[Mccaffrey]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
<name>
<surname><![CDATA[Finfer]]></surname>
<given-names><![CDATA[S]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[The Role Of Albumin As A Resuscitation Fluid For Patients With Sepsis: A Systematic Review And Meta-Analysis.]]></article-title>
<source><![CDATA[Critical Care Medicine]]></source>
<year>2011</year>
<volume>39</volume>
<numero>2</numero>
<issue>2</issue>
<page-range>386-91</page-range></nlm-citation>
</ref>
<ref id="B2">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Haynes]]></surname>
<given-names><![CDATA[G]]></given-names>
</name>
<name>
<surname><![CDATA[Navickis]]></surname>
<given-names><![CDATA[R]]></given-names>
</name>
<name>
<surname><![CDATA[Wilkes]]></surname>
<given-names><![CDATA[M]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Albumin Administration-What Is The Evidence Of Clinical Benefit? A Systematic Review Of Randomized Controlled Trials.]]></article-title>
<source><![CDATA[European Journal Of Anaesthesiology]]></source>
<year>2003</year>
<volume>20</volume>
<numero>10</numero>
<issue>10</issue>
<page-range>771-93</page-range></nlm-citation>
</ref>
<ref id="B3">
<nlm-citation citation-type="">
<person-group person-group-type="author">
<name>
<surname><![CDATA[More Huamán]]></surname>
<given-names><![CDATA[L. B]]></given-names>
</name>
</person-group>
<source><![CDATA[Hipoalbuminemia Como Predictor De Mortalidad En Pacientes Pediátricos Críticos Del Hospital Regional Cayetano Heredia-Piura. Período 2009-2013]]></source>
<year>2014</year>
</nlm-citation>
</ref>
<ref id="B4">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Pedersen]]></surname>
<given-names><![CDATA[T]]></given-names>
</name>
<name>
<surname><![CDATA[Møller]]></surname>
<given-names><![CDATA[A. M]]></given-names>
</name>
<name>
<surname><![CDATA[Gøtzsche]]></surname>
<given-names><![CDATA[P. C]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Human Albumin In Critically Ill Patients]]></article-title>
<source><![CDATA[Critical Care Medicine]]></source>
<year>2005</year>
<volume>33</volume>
<numero>5</numero>
<issue>5</issue>
<page-range>1183</page-range></nlm-citation>
</ref>
<ref id="B5">
<nlm-citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Press]]></surname>
<given-names><![CDATA[W]]></given-names>
</name>
</person-group>
<source><![CDATA[Numerical Recipes In C++. The Art Of Scientific Computing]]></source>
<year>2005</year>
<publisher-name><![CDATA[Cambridge University Press]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B6">
<nlm-citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Reviewers]]></surname>
<given-names><![CDATA[C. I. G. A]]></given-names>
</name>
</person-group>
<source><![CDATA[Human Albumin Administration In Critically Ill Patients: Systematic Review Of Randomised Controlled Trials.]]></source>
<year>1998</year>
<page-range>235-40</page-range><publisher-name><![CDATA[Bmj: British Medical Journal]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B7">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Velázquez Meza]]></surname>
<given-names><![CDATA[M]]></given-names>
</name>
<name>
<surname><![CDATA[Murillo Llanes]]></surname>
<given-names><![CDATA[J]]></given-names>
</name>
<name>
<surname><![CDATA[Tracy Gastélum]]></surname>
<given-names><![CDATA[C]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Hipoalbuminemia Como Factor Relacionado A Mortalidad En Pacientes Con Sepsis Del Hospital General De Culiacán.]]></article-title>
<source><![CDATA[Arch Salud Sin]]></source>
<year>2003</year>
<volume>7</volume>
<numero>1</numero>
<issue>1</issue>
<page-range>6-10</page-range></nlm-citation>
</ref>
<ref id="B8">
<nlm-citation citation-type="book">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Vincent J]]></surname>
<given-names><![CDATA[N. R]]></given-names>
</name>
<name>
<surname><![CDATA[Wilkes]]></surname>
<given-names><![CDATA[M]]></given-names>
</name>
</person-group>
<source><![CDATA[Morbidity In Hospitalized Patients Receiving Human Albumin: A Metaanalysis Of Randomized, Controlled Trials]]></source>
<year>2009</year>
<volume>32</volume>
<page-range>2029-38</page-range><publisher-name><![CDATA[Crit Care Med]]></publisher-name>
</nlm-citation>
</ref>
<ref id="B9">
<nlm-citation citation-type="journal">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Wilkes Mm]]></surname>
<given-names><![CDATA[N. R]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Patient Survival After Human Albumin Administration. A Meta-Analysis Of Randomized, Controlled Trials]]></article-title>
<source><![CDATA[Ann Intern Med]]></source>
<year>2001</year>
<volume>135</volume>
<numero>3</numero>
<issue>3</issue>
<page-range>149-64</page-range></nlm-citation>
</ref>
<ref id="B10">
<nlm-citation citation-type="">
<person-group person-group-type="author">
<name>
<surname><![CDATA[Zúñiga Cruz]]></surname>
<given-names><![CDATA[V]]></given-names>
</name>
</person-group>
<article-title xml:lang=""><![CDATA[Hipoalbuminemia Como Factor Pronóstico En Pacientes En Unidad De Cuidados Intensivos Pediátricos.]]></article-title>
<source><![CDATA[Arch Salud Sin]]></source>
<year>2005</year>
<volume>9</volume>
<numero>1</numero>
<issue>1</issue>
</nlm-citation>
</ref>
</ref-list>
</back>
</article>
