<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>2709-7927</journal-id>
<journal-title><![CDATA[Acta Médica del Centro]]></journal-title>
<abbrev-journal-title><![CDATA[Acta méd centro]]></abbrev-journal-title>
<issn>2709-7927</issn>
<publisher>
<publisher-name><![CDATA[Hospital Provincial Clínico Quirúrgico Universitario Arnaldo Milián Castro]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S2709-79272020000300313</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Factores de mal pronóstico en pacientes infectados por Staphylococcus aureus que ingresan en las salas de cuidados intensivos]]></article-title>
<article-title xml:lang="en"><![CDATA[Poor prognostic factors in patients infected with Staphylococcus aureus who are admitted to intensive care units]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Leiva Rabelo]]></surname>
<given-names><![CDATA[Yunior]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Céspedes Cárdenas]]></surname>
<given-names><![CDATA[Jarvis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Herrera Cartaya]]></surname>
<given-names><![CDATA[Carlos Enrique]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Chaviano Cárdenas]]></surname>
<given-names><![CDATA[Yailen]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Hospital Clínico Quirúrgico Universitario &#8220;Arnaldo Milián Castro&#8221;  ]]></institution>
<addr-line><![CDATA[Santa Clara Villa Clara]]></addr-line>
<country>Cuba</country>
</aff>
<aff id="Af2">
<institution><![CDATA[,Hospital Pediátrico Universitario &#8220;José Luis Miranda&#8221;  ]]></institution>
<addr-line><![CDATA[Santa Clara Villa Clara]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>09</month>
<year>2020</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>09</month>
<year>2020</year>
</pub-date>
<volume>14</volume>
<numero>3</numero>
<fpage>313</fpage>
<lpage>329</lpage>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S2709-79272020000300313&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S2709-79272020000300313&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S2709-79272020000300313&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  existen agentes biológicos patógenos que, en vez de establecer una relación simbiótica y armónica con el organismo humano, producen enfermedades y pueden provocar la muerte.  Objetivo:  determinar los factores de mal pronóstico en infecciones por Staphylococcus aureus.  Métodos:  se realizó un estudio descriptivo y prospectivo en las Salas de Medicina Intensiva del Hospital &#8220;Arnaldo Milián Castro&#8221; en el período comprendido entre septiembre de 2016 y junio de 2018.La población de estudio estuvo constituida por 114 pacientes con edades entre 19 y 82 años y la muestra por 82 pacientes. En el desarrollo de la investigación se emplearon métodos teóricos, empíricos y estadísticos.  Resultados:  se encontraron como factores de mal pronóstico la edad avanzada, las concentraciones mínimas inhibitorias por encima de 1mg/l, la escala Sepsis Related Organ Failure Assesment con 12 o más puntos, el score pronóstico APACHE II mayor de 20 puntos, la presentación inicial del cuadro clínico como choque séptico, el uso previo de antibióticos, comorbilidades como la diabetes mellitus, la infección pulmonar neumónica, la variedad staphylococica meticilin resistente, el uso de ventilación mecánica artificial y el uso previo de esteroides. El tipo de infección más frecuente fue la neumonía, seguida de las bacteriemias y de la infección de piel y partes blandas; el origen nosocomial y el extrahospitalario no tuvieron diferencias significativas.  Conclusiones:  el tipo de Staphylococcus aureus que con mayor frecuencia se aisló mediante cultivos bacteriológicos fue el resistente a la meticilina. La estadía prolongada en la UCI no resultó ser un factor de mal pronóstico.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  there are biological pathogenic agents that, instead of establishing a symbiotic and harmonious relationship with the human organism, produce disease and can cause death.  Objective:  to determine the factors of bad prognosis in infections by Staphylococcus aureus.  Methods:  a descriptive and prospective study was carried out in the Intensive Care Unit of the Arnaldo Milián Castro Hospital from September 2016 to June 2018. 114 patients between 19 and 82 years old made up the study population and 82 patients were included in the sample. Theoretical, empirical and statistical methods were used in the development of the research.  Results:  advanced age, minimum inhibitory concentrations above 1mg/l, Sepsis Related Organ Failure Assessment scale with 12 or more points, APACHE II prognostic score over 20 points, initial presentation of clinical picture as septic shock, previous use of antibiotics, comorbidities such as diabetes mellitus, pneumonic lung infection, methicillin-resistant staphylococic variety, use of artificial mechanical ventilation and previous use of steroids were found as bad prognostic factors. The most common type of infection was pneumonia, followed by bacteremias and skin and soft tissue infection; nosocomial and extrahospital origin did not differ significantly.  Conclusions:  the type of Staphylococcus aureus most frequently isolated by means of bacterial cultures was methicillin-resistant. Prolonged stay in the ICU was not a bad prognostic factor.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[pronóstico]]></kwd>
<kwd lng="es"><![CDATA[staphylococcus aureus]]></kwd>
<kwd lng="es"><![CDATA[cuidados críticos]]></kwd>
<kwd lng="en"><![CDATA[prognosis]]></kwd>
<kwd lng="en"><![CDATA[Staphylococcus aureus]]></kwd>
<kwd lng="en"><![CDATA[critical care]]></kwd>
</kwd-group>
</article-meta>
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