<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>0864-0300</journal-id>
<journal-title><![CDATA[Revista Cubana de Investigaciones Biomédicas]]></journal-title>
<abbrev-journal-title><![CDATA[Rev Cubana Invest Bioméd]]></abbrev-journal-title>
<issn>0864-0300</issn>
<publisher>
<publisher-name><![CDATA[ECIMED]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S0864-03002022000100010</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Manejo de la estenosis mitral durante el embarazo]]></article-title>
<article-title xml:lang="en"><![CDATA[Management of mitral stenosis during pregnancy]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vasallo Peraza]]></surname>
<given-names><![CDATA[Román]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Román Rubio]]></surname>
<given-names><![CDATA[Pedro Antonio]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Vázquez Hernández]]></surname>
<given-names><![CDATA[Gleiny]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gil Jimenez]]></surname>
<given-names><![CDATA[Yilena]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Meluzá Martín]]></surname>
<given-names><![CDATA[Mónica]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Gallinat Martín]]></surname>
<given-names><![CDATA[Yaima]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas de La Habana Hospital Ginecobstétrico Ramón González Coro ]]></institution>
<addr-line><![CDATA[ La Habana]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2022</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2022</year>
</pub-date>
<volume>41</volume>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S0864-03002022000100010&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S0864-03002022000100010&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S0864-03002022000100010&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN Las cardiopatías complican alrededor del 4 % de los embarazos; y representan la principal causa no obstétrica de muerte materna. Las lesiones valvulares tienen una alta prevalencia, siendo la estenosis mitral la de peor pronóstico durante el embarazo. El presente artículo tiene como objetivo exponer las recomendaciones del Servicio Nacional de Cardiopatía y Embarazo para el manejo de la estenosis mitral durante la gestación. Resulta crucial la evaluación de la anatomía valvular y la severidad de la enfermedad. Lesiones moderadas a severas deben ser tratadas con betabloqueadores cardioselectivos y comisurotomía percutánea electiva, si la anatomía es favorable. Si hay retención de volumen están indicados los diuréticos. Entre las drogas de uso obstétrico están contraindicadas las prostaglandinas, el nifedipino y el fenoterol. El momento de terminación del embarazo depende de la edad gestacional y de la aparición de signos de descompensación materna o fetal, en cuyo caso tienen indicación de cesárea.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT Heart disease complicates about 4% of pregnancies; and represent the leading non-obstetric cause of maternal death. Valvular lesions have a high prevalence, being mitral stenosis the one with the worst prognosis during pregnancy. This article aims to present the recommendations of the National Heart Disease and Pregnancy Service for the management of mitral stenosis during pregnancy. Evaluation of valve anatomy and disease severity is crucial. Moderate to severe injuries should be treated with cardioselective beta-blockers and elective percutaneous commissurotomy, if the anatomy is favorable. If there is volume retention, diuretics are indicated. Among the drugs for obstetric use, prostaglandins, nifedipine and fenoterol are contraindicated. The time of termination of pregnancy depends on the gestational age and the appearance of signs of maternal or fetal decompensation, in which case they have an indication for cesarean section.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[estenosis mitral]]></kwd>
<kwd lng="es"><![CDATA[embarazo]]></kwd>
<kwd lng="en"><![CDATA[mitral stenosis]]></kwd>
<kwd lng="en"><![CDATA[pregnancy]]></kwd>
</kwd-group>
</article-meta>
</front><back>
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