<?xml version="1.0" encoding="ISO-8859-1"?><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<front>
<journal-meta>
<journal-id>1028-4818</journal-id>
<journal-title><![CDATA[Multimed]]></journal-title>
<abbrev-journal-title><![CDATA[Multimed]]></abbrev-journal-title>
<issn>1028-4818</issn>
<publisher>
<publisher-name><![CDATA[Centro Provincial de Información de Ciencias Médicas]]></publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id>S1028-48182024000100008</article-id>
<title-group>
<article-title xml:lang="es"><![CDATA[Caracterización clínica epidemiológica de pacientes graves con infecciones adquiridas en la comunidad durante la COVID-19]]></article-title>
<article-title xml:lang="en"><![CDATA[Clinical epidemiological characterization of critical ill patients with community-acquired infections during COVID-19]]></article-title>
<article-title xml:lang="pt"><![CDATA[Caracterização Clínico-Epidemiológica de Pacientes Críticos com Infecções Comunitárias Durante a COVID-19]]></article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname><![CDATA[González Aguilera]]></surname>
<given-names><![CDATA[Julio César]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Martínez Tamayo]]></surname>
<given-names><![CDATA[Niubis Lázara]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Cabrera Lavernia]]></surname>
<given-names><![CDATA[Jorge Omar]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
<contrib contrib-type="author">
<name>
<surname><![CDATA[Álvarez Aliaga]]></surname>
<given-names><![CDATA[Alexis]]></given-names>
</name>
<xref ref-type="aff" rid="Aff"/>
</contrib>
</contrib-group>
<aff id="Af1">
<institution><![CDATA[,Universidad de Ciencias Médicas de Granma Hospital Provincial General &#8220;Carlos Manuel de Céspedes&#8221; ]]></institution>
<addr-line><![CDATA[Bayamo Granma]]></addr-line>
<country>Cuba</country>
</aff>
<pub-date pub-type="pub">
<day>00</day>
<month>00</month>
<year>2024</year>
</pub-date>
<pub-date pub-type="epub">
<day>00</day>
<month>00</month>
<year>2024</year>
</pub-date>
<volume>28</volume>
<copyright-statement/>
<copyright-year/>
<self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_arttext&amp;pid=S1028-48182024000100008&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_abstract&amp;pid=S1028-48182024000100008&amp;lng=en&amp;nrm=iso"></self-uri><self-uri xlink:href="http://scielo.sld.cu/scielo.php?script=sci_pdf&amp;pid=S1028-48182024000100008&amp;lng=en&amp;nrm=iso"></self-uri><abstract abstract-type="short" xml:lang="es"><p><![CDATA[RESUMEN  Introducción:  los pacientes graves requieren ingreso en las unidades de cuidados intensivos por infecciones adquiridas en la comunidad.  Objetivo:  caracterizar, desde el punto de vista clínico y epidemiológico, a los pacientes graves con infecciones adquiridas en la comunidad durante la COVID-19.  Métodos: estudio observacional, descriptivo, de serie de casos, en el periodo comprendido desde el 1ero de septiembre de 2020 hasta el 31 de enero de 2022. Se incluyeron a 277 pacientes. Se obtuvieron variables epidemiológicas y clínicas. El análisis estadístico se basó en medidas de resumen de la estadística descriptiva y de asociación.  Resultados:  el 52,7 % de los pacientes correspondieron al sexo femenino. La media de la edad fue 40,2 años (IC 95 %: 37,8-42,4). El Acute Physiology and Chronic Health Evaluation II (APACHE II) medio se estimó en 11, 8 (IC 95 %: 9,7-12,2). La escala Secuencial Organ Failure Assessment (SOFA) promedio fue de 1,8 (IC 95 %:1,4-2,2). El 31,7 % de los pacientes fueron hipertensos y 19,4 % diabéticos. La infección intraabdominal fue la localización principal (52,7 %), seguida de la neumonía (34,7 %). El 98,7 % tenía antimicrobianos al ingreso y el 26,3 % ventilación mecánica artificial.  Conclusiones:  los pacientes se caracterizan en su mayoría por pertenecer al sexo femenino, estar en la cuarta década de la vida, desarrollar alteraciones de sus sistemas fisiológicos y disfunción de órganos y tener hipertensión arterial y diabetes mellitus; infección intraabdominal o neumonía, así como requerir tratamiento con antimicrobianos, ventilación mecánica invasiva y drogas vasoactivas.]]></p></abstract>
<abstract abstract-type="short" xml:lang="en"><p><![CDATA[ABSTRACT  Introduction:  critically ill patients require admission to intensive care units due to community-acquired infections.  Objective:  to characterize, from a clinical and epidemiological point of view, critical ill patients with community-acquired infections during COVID-19.  Results:  52.7% of the patients were female. The mean age was 40.2 years (95% CI: 37.8-42.4). The mean Acute Physiology and Chronic Health Evaluation II (APACHE II) was estimated at 11.8 (95% CI: 9.7-12.2). The mean Sequential Organ Failure Assessment (SOFA) scale was 1.8 (95% CI: 1.4-2.2). 31.7% of the patients were hypertensive and 19.4% diabetic. Intra-abdominal infection was the main location (52.7%), followed by pneumonia (34.7%). 98.7% had antimicrobials on admission and 26.3% had artificial mechanical ventilation.  Conclusions:  the patients are mostly characterized by being female, being in the fourth decade of life, developing alterations in their physiological systems and organ dysfunction, and having high blood pressure and diabetes mellitus; intra-abdominal infection or pneumonia as well as requiring treatment with antimicrobials, invasive mechanical ventilation and vasoactive drugs.]]></p></abstract>
<abstract abstract-type="short" xml:lang="pt"><p><![CDATA[RESUMO  Introdução:  pacientes críticos necessitam de internação em unidades de terapia intensiva devido a infecções adquiridas na comunidade.  Objetivo:  caracterizar, do ponto de vista clínico e epidemiológico, pacientes graves com infecções comunitárias durante a COVID-19.  Métodos:  estudo observacional, descritivo, de série de casos, no período de 1º de setembro de 2020 a 31 de janeiro de 2022. Foram incluídos 277 pacientes. Foram obtidas variáveis epidemiológicas e clínicas. A análise estatística baseou-se em medidas-resumo de estatística descritiva e de associação.  Resultados:  52,7% dos pacientes eram do sexo feminino. A média de idade foi de 40,2 anos (IC 95%: 37,8-42,4). A média do Acute Physiology and Chronic Health Evaluation II (APACHE II) foi estimada em 11,8 (IC 95%: 9,7-12,2). A média da escala Sequential Organ Failure Assessment (SOFA) foi de 1,8 (IC 95%: 1,4-2,2). 31,7% dos pacientes eram hipertensos e 19,4% diabéticos. A infecção intra-abdominal foi a principal localização (52,7%), seguida de pneumonia (34,7%). 98,7% tinham antimicrobianos na admissão e 26,3% tinham ventilação mecânica artificial.  Conclusões:  a maioria dos pacientes é do sexo feminino, na quarta década de vida, desenvolve alterações de seus sistemas fisiológicos e disfunção orgânica, além de hipertensão arterial e diabetes mellitus; infecção intra-abdominal ou pneumonia, além de necessitar de tratamento com antimicrobianos, ventilação mecânica invasiva e drogas vasoativas.]]></p></abstract>
<kwd-group>
<kwd lng="es"><![CDATA[Infecciones adquiridas en la comunidad]]></kwd>
<kwd lng="es"><![CDATA[Epidemiología]]></kwd>
<kwd lng="es"><![CDATA[Paciente crítico]]></kwd>
<kwd lng="es"><![CDATA[Unidad de cuidados intensivos]]></kwd>
<kwd lng="es"><![CDATA[COVID-19]]></kwd>
<kwd lng="en"><![CDATA[Community-acquired infections]]></kwd>
<kwd lng="en"><![CDATA[Epidemiology]]></kwd>
<kwd lng="en"><![CDATA[Critical patient]]></kwd>
<kwd lng="en"><![CDATA[Intensive care unit]]></kwd>
<kwd lng="en"><![CDATA[COVID-19]]></kwd>
<kwd lng="pt"><![CDATA[Infecções adquiridas na comunidade]]></kwd>
<kwd lng="pt"><![CDATA[Epidemiologia]]></kwd>
<kwd lng="pt"><![CDATA[Paciente crítico]]></kwd>
<kwd lng="pt"><![CDATA[Unidade de Terapia Intensiva]]></kwd>
<kwd lng="pt"><![CDATA[COVID-19]]></kwd>
</kwd-group>
</article-meta>
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