The title page should include the full name of the institution sponsoring the manuscript or the institutional affiliation of the author; title of the article, full name(s) and surname(s) of each author with the Arabic consecutive number in the super-index identifying the authors at the end of each name; next at three spaces, the same Arabic number will be used in super-index when corresponds for every author; pointing out occupational profile, teaching rank, most important academic degrees and institutional affiliation, locality’s name and e-mail address of the main author and co-authors whenever possible.

Authors

Abstract and key words
A structured abstract up to 250 words in length follows, specifying the sections according to the type of article proposed. It must be written in impersonal style, without abbreviations, with references to the main text, footnotes or bibliography.
The purpose of the study or research will be indicated; basic procedures (selection of subjects matters; observation and analytical methods); the most important results (to offer specific data, and if possible statistical significance); and the main conclusions. Emphasis on new and important aspects of the study or observations must be placed.

Text
The text of observational and experimental articles is generally divided, though not by force, in the following sections: introduction, material and method, results, discussion and list of references. In large articles might be necessary to add subtitles within these sections, in those of the results and discussion over all, with the purpose of showing the clearest content.

Introduction

Material and method
Classify the type of research accurately. Describe the ways subjects under observation or participating in the experiments, target group (patients or lab animals, witnesses included) and the sample were chosen, explain the method used to chose them, if necessary. Identify the methods, the devices (name and address of the manufacturer in parentheses and its calibration or norm of quality control, to validate what you are measuring or weighting), and the procedures with sufficient details to other researchers can reproduce the results. Keep in mind the importance of this aspect to publish the proposed manuscript. Provide references of the methods proved, including those used for the statistical analysis when it is not a well-known method by the readers and briefly explain the methods previously published, but not well-known; describe the new methods or substantially modified, giving the reasons they were used and assessing its limitations. Identify all medications and chemical products used correctly, without omitting generic names, dosage and administration routes.

Ethics
In case of informing about human being-related experiments, lab animals or others, indicate the procedure used to ensure adherence to ethical guidelines of the committee (institutional or regional) that supervises human being- experimentations or with the Declaration of Helsinki-1975, amended in 1983.
Occasionally, detailed descriptions or photographs of individual patients, either whole or parts of the body (physiognomic features), constitute key documentation in the articles of medical journals. The use of such materials can lead to reveal the identity of the patient, sometimes indirectly, through a combination of apparently innocuous data.
Patients (and their families) have the right to remain anonymous in the clinical documentation published. Details that may identify patients should be avoided, unless they are essential for scientific purposes. Covering the eyes of the patients in the photographs may be an insufficient protection for the anonymity.
If the identification of patients is inevitable, it is compulsory to obtain the authorization of the patient with an inform consent, affirming that such consent was obtained and it must be submitted with the manuscript. Patients’ data will not be modified in order to protect his/her anonymity. The Journal reserves the right of publishing or not an article on the grounds that ethical or experimental standards have not been reached.

Results
The reason of the publication in the scientific articles is the basis of this heading. In some manuscripts a great number of results are obtained, which compels the author to choose the most important and accurate information according to the objectives proposed. In the text, tables, graphics and illustrations, will be used to present the results following a logic sequence and not more than the necessary, up to five. Do not repeat the data from the charts or the illustrations in the text: only highlight or sum up the most important observations. Write in accordance with the objectives, do not read the reader, guide the results achieved based on facts to understand them better. Results should be brief and clear. 

Discussion
The results of the research should be discussed by the author/authors. The interpretation of the facts where the author describes his/her competence and experience will be established. Putting emphasis on the new and important aspects that characterize the study and on the conclusions derived from these aspects in an appropriate order. Do not repeat details of the data or any other information previously presented in the introduction and results sections. To show the existing connection with the facts presented. In this section you should give explanation about the own opinions concerning the area under discussion; explain the meaning of the results and their limitations, comprising their consequences for a future research. Relate the observations to other pertinent studies. Establish the connection among the conclusions with the objectives of the study, but refrain from expressing general statements and extract conclusions which are not completely backed by data or omitted in the results. Do not claim for any type of origin or mention papers that are not concluded. Propose new hypotheses when there is a justification for them, but identify them clearly as such. This section includes, together with the discussion, the conclusions that summarize the assessment and repercussion of the manuscript, which must be inferred in the discussion. It is not necessary to present them apart, but should be mentioned in the abstract. When appropriate and significant some recommendations could be included.

Acknowledgement
It is a very important section to recognize persons and institutions that provided support to the development of the manuscript, but not reaching the condition of authorship. The collaborations that the authors wish to recognize can be specified, but do not justify authorship, the general support of the department in chief; those who have provided technical and material support specifying their disposition; and the financial relations that might raise conflict of interests.
The persons who provided intellectual collaborations to the article, but whose participation does not justify the authorship, can be cited by their names, adding function or type of collaboration; for example, “scientific advice”, “critical review of the proposal to conduct the study”, “data collection” or “participation in the clinical assay” or “literature review”. These persons should give permission to be named.
The authors will be responsible for obtaining the authorization of the persons named, since the readers can take for granted these persons support data and conclusions as well, therefore, they assume the responsibility as a declaration of authorship subsequently.The acknowledgement for technical assistance will have a separate paragraph as a testimony of gratitude for other contributions.

Bibliographic references

Vancouver's standards will be used for the references of the citations. Number references consecutively following the order mentioned first in the text, using Arabian number and super-index. Abstain from utilizing the summaries as references. Do not cite any persons as a reference or the unpublished observations neither the personal communications. On the other hand, you can insert in the text (in parentheses) the references to written, non-verbal communications in the case of the field of Social Sciences. You should include in the references the accepted articles although not yet published. In this case, indicate the journal's title and add "at the press" in parentheses. The information on manuscripts presented to a journal but not yet been accepted should be cited in the text as unpublished observations (in parentheses).

The original works should contain up to 20 citations, the reviews 25-50, and the case reports 10. Citations of published documents should be included with over 75% of updating. The bibliographic references on line must contain URL, dates of publication and access to consultation, so that they allow the editors and the readers to access to the referred article. The works not fitting to these instructions will return to the authors themselves. The accepted works will be processed according to the standards established by our Editorial Department. The uniform requirements before indicated are recommended to the authors in order to make easy the writing of the original. Our Editorial Department has the rights over the original works published in its journal. The source journal should be mentioned for total or partial reproduction and send one (1) printed issue to our address.

Pictures
Pictures and pictures should be elaborated or taken with professional quality, or present digital reproductions with picture quality. Pictures (as charts) should be sent or handed-in in the corresponding electronic files, in a format allowing the reproduction of high quality images in the journal’s electronic issue (i.e. jpeg or gif). The authors should verify these images have the required quality standards.

In the cases of radiographies, echographies and other diagnostic imaging techniques, and pictures of pathological specimen or microphotography, black-and-white or color, clear and satin reproductions should be used, generally in size 127 X 173 mm. Letters, figures and symbols included in the pictures should be clear and uniform, and have de appropriate size so that each character could be legible in the reduced version of the published article. The pictures should be explanatory, since many will be directly showed as slides for scientific presentations. However, the titles and detailed explanations should be included in inscriptions, not in the pictures’ bodies.

The microphotographies should have scale markers. Symbols, arrows, or letters included in microphotographies should stand out of the back.

If pictures of people are used, the latter should not be identifiable, or the corresponding authorization should be present in written form that allows it use. If possible, a specific permit should be obtained for the publishing of these materials.

The pictures footnotes should be consecutively numbered, following the order by which they have first been cited in the text. If a previously published picture is used, the original source should be mentioned, and the copyright document should be sent with the manuscript, with the authorization for reproducing the material. At least it is a document of public view, this authorization is required no matter which the publishing house or the authors are.

The pictures should include the inscription below, after the source. When symbols, arrows, numbers or letters are used to identify parts of the picture, their meaning should be clearly explained in the inscriptions. The inner scale of the picture should also be explained.

Units of measurement
Metric units (metres, kilograms, or litters) or their decimals should be used for length, height, mass, and volume measures. Temperature should be expressed in Celsius degrees. Blood pressure should be measures in millimetres of mercury (mmHg). All the results of laboratory clinical tests should be given in IS-permitted units. To use any traditional unit, they should be written in parentheses. E.g.: glycemia: 5, 55 mmol/L (100mg/100 mL).

Abbreviations and symbols
Only common abbreviations should be used; the use of little usual abbreviations could be extremely confusing for the readers. The authors must avoid the use of abbreviations in the work title. The first time that an abbreviation appears in the text must be preceded for the complete term one refers to, except in the case of common units of measurement. The works not fitting to these instructions will be mailed to the authors so that they will be able to pick up in a period of ten days, after this time they will not be kept.

Some important aspects to have in account for writing the works:

Write clearly and concisely. Use the impersonal style.
Avoid the abuse of the passive voice.
Take care of the use of the capital letter
Remember using the agreement between gender, number and subject.
Do not overuse participles and gerunds.
Avoid the incorrect use of prepositions.
Avoid the long sentences and the excessive subordinations.
Utilize the convenient punctuation marks to separate enunciates correctly.

Original article