Abstract

DEL POZO JEREZ, Haydeé Aurora; HERNANDEZ DIAZ, Lázaro; LEIVA SUERO, Lizette Elena  and  GONZALEZ MONTERO, Andrés. Dinitrato de isosorbide sublingual en la urgencia hipertensiva. Rev cubana med [online]. 1998, vol.37, n.1, pp. 13-17. ISSN 1561-302X.

The use of sublingual isosorbide dinitrate in the hypertensive urgency was investigated. It was also established a correlation with nifedipine, whose efficacy has been proved to this end. 80 patients with this diagnosis were studied and divided at random into 2 groups, who received 10 mg of nifedipine or isosorbide dinitrate and a second dosage if their pressure was not controlled 45 minutes after the first dosage. With the first dosage of isosorbide dinitrate a higher number of patients were controlled (n = 29) compared with nifedipine (n = 19). 36 patients were controlled with the second dosage of both drugs. Nifedipine caused mild cephalalgia. To conclude, isosorbide dinitrate proved to be an efficient drug, easy to administer and with a few side effects in the treatment of hypertensive urgency. It may be another alternative for urgency services.

Keywords : ISOSORBIDE DINITRATE [administration & dosage]; NIFEDIPINE [administration & dosage]; EMERGENCY SERVICE; HOSPITAL; ADMINISTRATION, SUBLINGUAL.

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