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Revista Cubana de Medicina
On-line version ISSN 1561-302X
Abstract
DORTA GURIDI, Zaily et al. Tolerance to treatment with standard interferon and ribavirin in patients presenting with cirrhosis from hepatitis C. Rev cubana med [online]. 2010, vol.49, n.2, pp. 0-0. ISSN 1561-302X.
In treatment of compensating hepatic cirrhosis of viral etiology the maintained viral response with Interferon and Ribavirin is minor and it is accompanied of a greater frequency of adverse effects in relation to non-cirrhotic patients. However, due to the scarce therapeutical options for this group of patients and the need to retard the appearance of complications, was the reason of present paper. Authors present the results from a group of 36 patients diagnosed with hepatic cirrhosis from HCV in A Child's stage included in multicenter clinical trials, sponsored by the Institute of Gastroenterology; patients received a therapeutical scheme of Interferon alfa-2b plus Ribavirin during 48 weeks assessing their tolerance by clinical and hematologic adverse events. Results demonstrate that this treatment alternative is safe and well-tolerated.
Keywords : Treatment; hepatic cirrhosis by hepatitis C virus.