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Revista Cubana de Hematología, Inmunología y Hemoterapia

On-line version ISSN 1561-2996

Abstract

GUERREIRO HERNANDEZ, Ana M.; VILLAESCUSA BLANCO, Rinaldo  and  MORERA BARRIOS, Luz M.. Evaluation of a latex agglutination method for the detection of rheumatoid factor. Rev Cubana Hematol Inmunol Hemoter [online]. 2008, vol.24, n.1, pp. 0-0. ISSN 1561-2996.

An agglutination method with latex of national production (Centis) was evaluated to detect the rheumatoid factor by using a turbidimetric assay with latex (Spin React, Spain) as a reference procedure in a group of patients with rheumatoid arthritis. The results obtained in the evaluated method (sensitivity 93 %, specificity 80 %, positive predictive value 97.6 %, negative predictive value 57.1 %, and a detection limit of 15 UI/mL) showed its quality and usefulness.

Keywords : Latex agglutination; rheumatoid arthritis; rheumatoid factor; turbidimetry.

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