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Revista Cubana de Hematología, Inmunología y Hemoterapia

On-line version ISSN 1561-2996

Abstract

GOMEZ BAUTE, Rafael et al. Orbit tumor as an uncommon way of presentation of a no-Hodgkin extranodal lymphoma of marginal zone. Rev Cubana Hematol Inmunol Hemoter [online]. 2010, vol.26, n.1, pp. 76-82. ISSN 1561-2996.

The no-Hodgkin lymphomas (NHL) accounted for the half of orbit tumor; however, its incidence in our environment is very uncommon. This is the case of a white female patient aged 52 with personal pathological backgrounds of high blood pressure without other relevant data in questioning, referred to consultation due to epiphora and a discrete palpebral ptosis of right eye accompanied by hard and fixed tumor in inferior medial of right orbita. Main laboratory tests were normal. In magnetic resonance (MR) it was demonstrated the presence of a 2 x 1 cm tumor with irregular borders in relation to posteroinferior wall of right orbit. A lesion biopsy was carried out with diagnosed as a primary NHL con immunophenotype compatible with a lymphoproliferative process. We conclude that this case is a primary orbit NHL of principal zone with leukemic expression of monocytic B cells in IVA state. We performed 8 cycles of CHOP with a partial response. Subsequently, we passed to a second-line maintained scheme consistent in Rituximab-Fludarabine-Cyclophosfamide-Dexamethasone.

Keywords : No-Hodgkin lymphoma; orbit tumor.

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