Abstract

MENA-PEREZ, Rafael; FERNANDEZ-DELGADO, Norma  and  GARMENDIA-GARCIA, Fermín. Impact of cell therapy in carpal tunnel syndrome. Rev Cubana Hematol Inmunol Hemoter [online]. 2012, vol.28, n.1, pp. 59-69. ISSN 0864-0289.

We present a small series of patients with carpal tunnel syndrome who underwent implantation of autologous mononuclear cells from peripheral blood to assess the feasibility and safety of these in the sixth month after that procedure. We included 6 patients treated at the Department of Orthopedic in The Enrique Cabrera General Teaching Hospital. The improvement in symptoms began one week after the procedure. Pain and cramping were the first to disappear, the improvement increased one month after and it was maintained until the sixth month of evaluation. The clinical-neurological manifestations improved in 80.3 % of patients, as well as in the study of motor and sensory conduction. There was no reaction to the implant. The improvement of the clinical manifestations and conduction studies support the mediation of stem cells in inflammatory action, revascularization and remyelination of the median nerve, which is expressed in the positive responses obtained.

Keywords : stem cells; carpal tunnel syndrome; regenerative medicine; cell therapy.