Abstract

FAGUNDO, Juan Carlos Jaime; CESPEDES ROSALES, Luis Enílber; ROQUE GARCIA, Wilfredo  and  LEIVA PERDOMO, Yanitza. Hematologic manifestations, pathogenesis and laboratory tests in Ebola virus disease. Rev Cubana Hematol Inmunol Hemoter [online]. 2015, vol.31, n.4, pp. 0-0. ISSN 1561-2996.

Ebola virus disease is an often-fatal infection caused by one of the five strains of the Ebola virus that affects both animals and humans. The fatality rate can reach 90% and since its detection, there have been several outbreaks, including the last in April 2014. One of the most important manifestations is the hemorrhagic syndrome which usually occurs in the late stages of the disease, condition that is not present in all affected patients. Major hematologic manifestations in this entity, as well as some aspects of its pathogenesis and useful laboratory tests in the management of these patients are described.

Keywords : Ebola virus; outbreak; hematological irregularities; hemorrhagic fever; disseminated intravascular coagulation; lymphopenia.

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