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Revista Cubana de Investigaciones Biomédicas
On-line version ISSN 1561-3011
Abstract
TENORIO BORROTO, Esvieta; AGUILA JIMENEZ, Edisleidy and TRIMINO, Caridad. Evaluación dermotoxicológica de la hexamina. Rev Cubana Invest Bioméd [online]. 2002, vol.21, n.1, pp. 5-8. ISSN 1561-3011.
The possible irritant effect of a formulation that will be used as a deodorant and that contains methenamine, a urinary antiseptic, as an active principle, is evaluated. This formulation was applied by ophthalmic route to 6 New Zealand breed rabbits for 7 days. The assessments are based on the macroscopic observations of the possible adverse effects appearing in the skin structures.
Keywords : METHENAMINE [adverse effects]; DRUG SCREENING [methods]; TOXICITY TESTS.