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Revista Cubana de Medicina General Integral
On-line version ISSN 1561-3038
Abstract
TORRES, Virginia; HERNANDEZ CUELLAR, María Victoria; AMARO RELOVA, Roberto and TORRES LIMA, Ana María. Inmunoterapia en la Artritis Reumatoidea. Rev Cubana Med Gen Integr [online]. 1999, vol.15, n.1, pp. 41-45. ISSN 1561-3038.
The immunotherapy in the rheumatoid arthritis includes the use of molecules produced by cells of the immune system or that take part in inflammatory reactions as well as recombinant forms of such molecules. The development of monoclonal antibodies led to the trial of anti T cell therapies without encouraging results. The treatment with anti-tumor necrosis factor alpha monoclonal antibodies is promising at present, as well as the use of recombinant citokines that condition the predominance of type II helper-T-cells. However, in the future the use of gene therapy could be the most powerful weapon to treat rheumatoid arthritis
Keywords : IMMUNOTHERAPY; ARTHRITIS, RHEUMATOID [therapy]; ANTIBODIES, MONOCLONAL.