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MEDISAN
On-line version ISSN 1029-3019
Abstract
MONTOYA PEDRON, Arquímedes; PEREZ ABALO, María C; GALAN GARCIA, Lídice and SANCHEZ HECHAVARRIA, Miguel E. Brain sources localizing of multiple frequency auditory steady state response modulated at 40 hertz. MEDISAN [online]. 2011, vol.15, n.8, pp. 1063-1071. ISSN 1029-3019.
The involved neural bases were studied in the generation of the auditory steady state response, obtained by stimulation with 40 hertz multiple frequency amplitude modulate tones, for which a high space resolution registration protocol was designed, the Bayes`method was applied to estimate their neurogenerators and restrictions were previously defined to focus the initial calculation from the primary activation areas to the auditory system. The results are able to detect generating sources at the level of the upper temporal lobe of both hemispheres; but the cortical activation is not symmetrical and an interhemispheric lateralization effect is registered, with activation of the contralateral upper temporal lobe to the stimulated ear as a response to tones of 500 hertz, while for the tones of 4 000 hertz, the cortical activation level is higher at the level of the ipsilateral upper temporal lobe to the stimulated ear. The present results obtain a new methodology for the evaluation of the auditory system that can be applied in the characterization of the cortical reorganization and neuroplasticity in severe neurosensory hearing loss and other sensory deprivations.
Keywords : auditory evoked potentials; brain generators; Bayes´method; hertz.