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MEDISAN
On-line version ISSN 1029-3019
Abstract
INFANTE CEDENO, Reydienis Ricardo; IBAR SANCHEZ, Elizbieta and GARCIA CESPEDES, María Eugenia. Predictive factors for bone metastasis in patients with prostate cancer. MEDISAN [online]. 2023, vol.27, n.5 Epub Oct 31, 2023. ISSN 1029-3019.
Introduction:
Prostate adenocarcinoma is considered one of the most frequent neoplasms in men over 60 years, and bone metastasis constitutes one of the complications with the worst prognosis.
Objective:
Estimate the predictive factors for bone metastasis in patients with prostate cancer.
Methods:
An analytic study of 73 patients with prostate cancer was carried out. They were assisted at Conrado Benítez Cancer Hospital in Santiago de Cuba during 2018-2022. The variables analyzed included: age, skin color, clinical manifestations, onset time of bone metastasis, degree of cellular differentiation, prostate-specific antigen level and imaging diagnosis.
Results:
In the series there was a prevalence of the 60-69 age group (50.7%) and the average age was 67 years; also, dark skinned patients, bone pain as more frequent symptom and imaging diagnosis of bone metastasis by computerized axial tomography prevailed (48.0%). A proportional increase of prostate-specific antigen values and Gleason punctuation was observed in relation to the metastasis onset.
Conclusions:
The predictive factors for estimating the presence of bone metastasis in patients with prostate cancer are the advanced age, black skin color and prostate-specific antigen values above 20 ng/mL.
Keywords : prostate cancer; bone metastasis; predictive factor; prostate-specific antigen.