Abstract

RIBALTA GARCIA, Gricel; ARMENTEROS PEREZ, Miguel Ángel  and  OJEDA ODELIN, Aymee. IgA deficiency. Medicentro Electrónica [online]. 2023, vol.27, n.3  Epub Sep 01, 2023. ISSN 1029-3043.

Selective IgA deficiency is defined as the partial or total absence of IgA in the serum, but normal levels in the rest of the immunoglobulins. We present a female patient aged 1 year and 7 months, of non-consanguineous parents, who had a negative family pathological history for genetic diseases or congenital defects and IgA deficiency. Immunological studies showed a high IgA deficiency, hence the diagnosis was defined as congenital immunodeficiency due to selective IgA deficiency or common variable immunodeficiency (genetic disorder resulting from monogenic inheritance); a quantification of the IgG subclass was also performed in order to determine if it was a mutation in the same defective gene. The patient evolved satisfactorily with the treatments received; the IgA values remained null, but this was not the case with the rest of the immunoglobulins.

Keywords : IgA deficiency; immunoglobulins; congenital abnormalities.

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