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Medicentro Electrónica

On-line version ISSN 1029-3043

Abstract

CRUZ ABASCAL, Rafael Enrique et al. Oncoproliferative diseases in kidney transplant recipients. Our experience. Medicentro Electrónica [online]. 2024, vol.28, n.1  Epub Mar 01, 2024. ISSN 1029-3043.

Introduction:

cancer entails a mortality of up to 12 % in transplanted patients and is considered the third leading cause of morbidity and mortality in recipients who are susceptible to develop oncoproliferative diseases in the long term.

Objective:

to describe the incidence of neoplasms in renal transplant recipients.

Methods:

we carried out a descriptive and longitudinal study including 15 functioning renal transplant recipients who were diagnosed with malignant neoplasms in different locations in the Nephrology service at “Arnaldo Milián Castro” Clinical and Surgical University Hospital in Santa Clara, Villa Clara between January 2017 and June 2023.

Results:

males and white skin color predominated: 53.3 % and 73.3% respectively, with post-transplant time greater than three years in 12 patients (80 %). The history of cytomegalovirus exposure represented 80 %; bacterial infection of the respiratory and digestive tracts was the most frequent.

Conclusions:

cervicouterine intraepithelial neoplasia, colon cancer with liver and brain metastases were the most frequent and treated with surgery chemotherapies or both according to the surgical criteria in each case; however, mortality was elevated. Cervical intraepithelial neoplasia predominated in a 26.6 %. Mortality was high and survival was lower in males, without exceeding two years after the diagnosis.

Keywords : kidney transplantion; kidney neoplasms; nephrology.

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