Abstract

SAGUE LARREA, Jorge Luis; PROANO LUCERO, Silvia  and  DOIMEADIOS RODRIGUEZ, Zulma. Prostate-specific antigen role in mass or individual screening. ccm [online]. 2019, vol.23, n.1, pp. 210-222. ISSN 1560-4381.

Screening for prostate cancer with prostate-specific antigen (PSA) has been used for many years. Nevertheless in present times, many randomized trials call into question its usefulness.

In this work, we have evaluated the history of PSA, as a method of diagnosis in prostate cancer and its role in screening at this time. For this, we have made a worldwide review about the main opinions, clinical trials and meta-analysis, related to the current value of the screening for prostate cancer early detection. The bibliographic search was done main in Medline (ERSPC) as well as those of Gothenburg, which have shown a slight decrease in mortality from 55 to 69 age groups, during their 13 years follow-up. Other trials about the benefits of early detection are still in doubt; taking into account quality of life damage, overdiagnosis risks and treatment complications.

Keywords : antigen; PSA; prostate cancer; screening.

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