Abstract

ALVAREZ PRATS, Manuel  and  TRIANA MANTILLA, María Eugenia. Behaviour of the uric acid in the general casuistic and in patients with peripheral vascular disease. Rev Cubana Angiol Cir Vasc [online]. 2015, vol.16, n.1, pp. 37-43. ISSN 1682-0037.

Objective: to determine the behaviour of the uric acid in a general casuistic and in the patients with vascular periphery disease and calculating the prevalence of hyper-uricaemia. Methods: a descriptive study in 464 patients assisted at aboratory of Biochemistry of the Institute of Angiology and Vascular Surgery during the month of may of 2013 and in the 85 patients with vascular periphery disease was analyzed. Uric acid quantified in alls with a commercial game of enzymatic reagent. The hyper-uricaemia determined itself when taking the following values into account: 415.4 µmol/ L for man and 339.0 µmol/L for woman. Was calculated the total prevalence of hyper-uricaemia and tight-fitting according to sex. Results: the concentration of uric acid in the sample was of 320.3 µmol/L (95 % CI: 310; 330,6) With difference between man and woman (354.1 vs. 29,3 µmol/L, p= 3,74 x 10-9). The patients with diabetic macroangiopathy had high concentration of uric acid (339.5 µmol/L) within significant difference with general casuistic. The prevalence of hyper-uricaemia was of the 27.6 %; of her the 24.8 % for the masculine sex and the 30.0 % for the feminine. Conclusion: it is done called the reflection on this parameter, what has high prevalence, which must not be indicated like routine; since it can be a biomarker of vascular periphery disease as it is for the arterial hypertension, renal function and gout.

Keywords : uric acid; hiper-uricaemia; vascular periphery disease.

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