Abstract

LEON VAZQUEZ, Alfonso R; MARTINEZ GONZALEZ, Larisa  and  ORIZONDO PAJON, Sergio A. Uso del ácido épsilon aminocaproico en cirugía torácica electiva. Rev Cubana Cir [online]. 2001, vol.40, n.2, pp. 112-118. ISSN 1561-2945.

A randomized, prospective and comparative clinicotherapeutic trial was conducted as part of a non-observational study that included 60 patients who underwent elective thoracic surgery in order to evaluate the effectiveness of epsilon aminocaproic acid (EACA) in connection with the decrease of postoperative bleeding and homologous transfusions in this period, as well as to describe its potential undesirable reactions. It was found that the quantity of blood collected in the postoperaive period was much lower in the group treated with EACA than in the control group, both at 6.00 and at 24.00 hrs postintervention. The units of red blood cells transfunded in the transoperative period were similar in both groups, but the quantity of red blood cells administered in the postoperative was significantly lower in the study group, as well as the proportion of patients requiring homologous transfusions in this group. There were no differences between both groups as for undesirable reactions

Keywords : THORACIC SURGERY [complications]; THORACIC SURGERY [drug therapy]; 6-AMINOCAPROIC ACID [therapeutic use]; ANTIFIBRINOLYTIC AGENTS [therapeutic use]; BLOOD TRANSFUSION.

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