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Revista Cubana de Cirugía
On-line version ISSN 1561-2945
Abstract
LOPEZ RODRIGUEZ, Marta Sofía and AREU REGATEIRO, Alejandro Jesús. Shock, ¿qué hay de nuevo?. Rev Cubana Cir [online]. 2003, vol.42, n.1, pp. 0-0. ISSN 1561-2945.
Shock is a commom syndrome originated by different causes that starts with a decrease of histic perfusion, where macrocirculation has a critical function. In recent studies, emphasis has been made on the fact that therapeutics should be immediate in the face of this life menace and should include respiratory support, circulatory support, metabolic monitoring, hemodynamics and specific treatment. The use of crystalloids versus colloids is controversial and depends on the medical criterion. The usefulness of amrinone (ionotrope), mainly in patients with septic shock, and of vasopressin as a vasopressor is proved. The monitoring of the plasmatic concentration of the lactic acid is necessary due to its relation with mortality from shock. The mortality from septic shock is still high, in spite of the multiple investigations made. The recent utilization of nitric oxide synthase (S methyl-isothiourea) inhibitors seems to be encouraging on inhibiting the inductible isoform (iNOS), the same as immunotherapy, but new studies are necessary to evaluate its clinical efficiency
Keywords : SHOCK [mortality]; SHOCK [therapy]; SHOCK, SEPTIC [mortality]; SHOCK, SEPTIC [therapy]; VENTILATION-PERFUSION RATIO; COMBINED MODALITY THERAPY; COLLOIDS [therapeutic use]; IMMUNOTHERAPY.