Abstract

DE LA PARTE PEREZ, Lincoln. Value of the aminocaproic epsilon acid in pediatric cardiovascular anesthesia. Rev Cubana Cir [online]. 2005, vol.44, n.1, pp. 0-0. ISSN 1561-2945.

The persistent bleeding after the extracorporeal circulation is one of the most frequent complications in cardiovascular surgery and implies the administration of repeated blood transfusions with a significant increase of morbidity and mortality. The therapeutic approach of this complication includes different measures, among which the administration of antifibrinolytics plays an important preventive role. A study of 50 children that underwent cardiovascular surgery under extracorporeal circulation performed at the Heart Center of “William Soler” Children's Hospital from January 2001 to February 2002, was conducted. 100 mg/kg of aminocaproic epsilon acid were administered before the extracorporeal circulation as an initial dose for 20 min. It was maintained then at a rate of 15 mg/kg/h until the closure of the skin. No complications were observed, in spite of the fact that it was used at high doses at the beginning. There was neither prolonged bleeding nor evidence of marked coagulation disorders, which may be attributed to the preventive measures that were taken

Keywords : Antifibrinolytics; aminocaproic epsilon acid; pediatric cardiovascular anestesia.

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