Abstract

Results of the inductive treatment of locally advanced non-small cell lung cancer. Rev Cubana Cir [online]. 2007, vol.46, n.3, pp. 0-0. ISSN 1561-2945.

Forty-four patients with locally advanced non-small cell lung cancer, who had received platinum-based radiochemotherapy for surgery induction, were assessed. Nine patients (20,5 %) had complete radiological responses and 17 patients(38,6 %) achieved a reduction higher than or equal to half of the tumor´s initial diameter in its greater axis. The complete or partial radiological response was predictive of resectability (p = 0,048) and associated to better pathological responses (p = 0,031). Four patients (9,9 %) reached histological remission whereas 25 (31,3 %) had partial pathological responses. Pathological sterilization of the ganglionary groups was observed in 23 (74,1 %) of 31 affected subjects. Complete resection was applied in 39 patients (88,6 %), morbidity was acceptable and no post-operative deaths occured. The neoadjuvant treatment was useful for this group of patients since it induced the pathological response and also increased the resectability possibilities

Keywords : neoadjuvant treatment; inductive treatment; platinum-based concurrent radiochemotherapy.

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