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Revista Cubana de Estomatología
On-line version ISSN 1561-297X
Abstract
DELGADO FERNANDEZ, Rafael; URBIZO VELEZ, Joaquín; RODRIGUEZ SOSA, Víctor and IGLESIAS RODRIGUEZ, Enrique. Histological evaluation of tricalcium beta phosphate (Biograft-G) as bone implant. Rev Cubana Estomatol [online]. 2010, vol.47, n.2, pp. 124-133. ISSN 1561-297X.
With the aim to determine the histocompatibility, osteoconduction properties and biodegradation of synthetic tricalcium beta phosphate (Biograft-G) obtained in the Biomaterials Centre of Havana University we developed an experimental study using 10 Beagle dogs in which were placed Biograft-G implants in femur and jaw bones with their corresponding controls. The animals were sacrificed in three different periods: 3, 6 months, one and two years time of implantation. Block bone samples were obtained, fixed in 10 % neutral formalin, decalcified and processed with the paraffin inclusion method and stained with Haematoxylin and Eosin. The study was carried out with optical microscope. We conclude that, according to the results obtained, Biograft-G is a histocompatible, osteoconductor and biodegradable material.
Keywords : Tricalcium beta phosphate; implant.