Abstract

LEDON, Nuris et al. Efectos antipsoriásico, antiinflamatorio y analgésico del propoleo rojo colectado en Cuba. Rev Cubana Farm [online]. 1996, vol.30, n.1, pp. 0-0. ISSN 1561-2988.

The antipsoriatic, antiinflammatory, and analgesic effects of a red propolis extract, were assessed. This extract induces the formation of a granular layer in the mouse tail test, used as a model for psoriasis. Propolis at a 50 mg/kg dose (oral) showed antiinflammatory activity in the cotton granuloma model in rats, as well as in the capillary permeability test in rats peritoneum at a 10 mg/kg dose. Propolis extract (25 mg/kg, oral) presented analgesic properties in the acetic acid stretching model, while the 40 mg/kg dose was effective in the hot plate test in mice. These results demonstrate evidence about the potential usefulness of red propolis in inflammatory disorders, and particularly, in the management of psoriasis.

Keywords : PROPOLIS [therapeutic use]; ANTIINFLAMMATORY AGENTS [therapeutic use]; ANALGESICS [therapeutic use]; ANTIPSORICS [therapeutic use]; CLINICAL TRIALS; RATS; INBRED STRAINS; MICE; CUBA.