Abstract

FERNANDEZ MONAGAS, Sol A; RODRIGUEZ ALBADALEJO, María D; BILBAO REVOREDO, Ofelia  and  NIETO ACOSTA, Olga M. Quitina y carboximetilquitosana como agentes desintegrantes. Rev Cubana Farm [online]. 1998, vol.32, n.2, pp. 120-124. ISSN 1561-2988.

A comparative study of chitin and carboxymethylchitosan as disintegrating agents was wade made. The influence exerted bu tje method used in the preparation of the tablets on the disintegrating activity of both polymers was evaluated. Chitin proved to have good characteristics as a disintegrating agent independently of the method used to make tablets. The disintegrating activity of carboxymethylchitosan was affected by the granulation process.

Keywords : CHITIN [analogs & derivatives]; CHEMISTRY, PHARMACEUTICAL [methods]; TABLETS.

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