Abstract

BENITEZ HECHAVARRIA, Ernesto et al. Validation of an analytical method for the quantitative determination of parabens in aluminum hydroxide gel. Rev Cubana Farm [online]. 2006, vol.40, n.2, pp. 0-0. ISSN 1561-2988.

The prospective assessment of a method developed for the quantification of methyl/propyl paraben in aluminum hydroxide gel by reverse-stage high resolution liquid chromatography on RP18 column (25*0.4 cm), and with UV detector visible at 254 nm, was made. The specificity, lineality, accuracy, exactness and chromatographic adequacy were evaluated The results obtained showed that the method meets the specifications established for each evaluated parameter, which indicates that it is a rapid, safe and reliable method for the quantitative determination of the parabens in this gel

Keywords : Parabens; high resolution liquid chromatography (HRLC); suspension.