Abstract

AL-SHAGHDARI, Ahmed; BELLO ALARCON, Adonis  and  CUESTA-RUBIO, Osmany. Determination of biflavonoids in different parts of Garcinia bakeriana (Urb) Borhidi. Rev Cubana Farm [online]. 2014, vol.48, n.2, pp. 307-315. ISSN 0034-7515.

Introduction: previous studies have revealed genus Garcinia to be a rich source of secondary metabolites, namely xanthones, acylphloroglucinols and bioflavonoids. However, the chemical composition of Cuban species in this genus is almost unknown. Objective: to determine the presence of 11 biflavonoids in Garcinia bakeriana leaves, latex and stem bark. Methods: leaves, latex and stem bark extracts of G. bakeriana were compared by using an ultra high performance liquid chromatography method (UPLC) and 11 biflavonoid standards. Results: biflavonoids GB-1A, GB-2A, GB-2A glycoside, morelloflavone glycoside, 4´´´methoxy- I3,II8-biapigenin, I3,II8-biapigenin, amentoflavone y 4´´´-methoxyamentoflavone were detected as components in G. bakeriana leaves and stem bark. Conclusions: G. Bakeriana species has biflavonoids as components of its leaves and stem bark. The work methodology described in this paper helps to expand the knowledge about the chemical composition of the Cuban flora and may represent a rapid method with low dissolver consumption for the comparative study of poorly distributed and non abundant Cuban endemic species.

Keywords : Garcinia bakeriana; biflavonoids; UPLC.

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