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Revista Cubana de Farmacia

On-line version ISSN 1561-2988

Abstract

ALBERT CABRERA, Marco J et al. Pathogenesis and current treatment of Alzheimer's disease. Rev Cubana Farm [online]. 2014, vol.48, n.3, pp. 508-518. ISSN 1561-2988.

Alzheimer disease is a neurodegenerative illness that manifests as cognitive deterioration and behavioral disorders. It holds the 6th place, like dementia, in the list of main causes of death in Cuba. There is no effective treatment to stop progression of Alzheimer's disease. However, some therapies manage to halt or to slow at least temporarily the cognitive, functional and behavioral deterioration of the disease. This paper presented an updated review on the pathological mechanisms and the drugs used in the treatment of Alzheimer patients, using MEDLINE database.

Keywords : Alzheimer; dementia; senile dementia; cognitive deterioration; beta-amyloid plaques.

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