Abstract

PINOL JIMENEZ, Felipe N.  and  PANIAGUA ESTEVEZ, Manuel. Mediadores bacterianos de la inflamación en la gastritis crónica por Helicobacter pylori. Rev cubana med [online]. 1999, vol.38, n.4, pp. 276-283. ISSN 1561-302X.

It is known that the chronic inflammation of the stomach is a very controversial topic in medical practice from the clinical, endoscopic, radiological and histological points of view. A detailed investigation is being carried out to reveal the different physiopathological mechanisms causing the histic damage of the stomach. With the discovery and characterization of Helicobacter pylori and its close relationship with type B chronic gastritis and gastroduodenal ulcers, the natural history of these affections and their therapeutic approach have changed radically. The different processes that occur after it reaches the stomach are explained in this paper. The actions produced by the bacterial mediators (proinflammatory and antigenic) that take part in the histic damage considered in the clinic as gastritis are also stressed here. This is a topic of great interest for clinicians, gastroenterologists and doctors in general, who are interesed in searching new treatments not only to eradicate the bacteria but also to regulate the action of the bacterial mediators to attain an adequate repair of the gastric mucosa.

Keywords : INFLAMMATION MEDIATORS [physiology]; GASTRITIS [physiopathology]; HELICOBACTER PYLORI..

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