Abstract

GOMEZ VIERA, Nelson; MONTEAGUDO TORRES, Marisol; DE CASTRO ARENAS, Raúl  and  RUIZ GARCIA, Dania. Complicaciones neurológicas en pacientes con linfomas. Rev cubana med [online]. 2000, vol.39, n.2, pp. 75-87. ISSN 1561-302X.

A prospective and descriptive study was carried out in 270 patients diagnosed of lymphoma, admitted in Hematology Service of "Hermanos Ameijeiras" Clinical Surgical Hospital in Havana City, Cuba, from March 1, 1996 to December 31, 1998, to assess neurologic complications. 26 patients presenting with neurologic complications were detected. From 188 sick persons with non-Hodgkin's lymphoma, 12,2 % had neurologic manifestations. In these patients, leptomeninges infiltration was the more frequent neurologic complication. In 82 patients with Hodgkin's disease, only 3,6 % had neurologic alteration and Herpes zoster infection was the commonest one. We found higher percent of patients with syndromes attributable to spinal cord compression and to craneal pars disturbance, headache was commonest and motor deficit the more frequent one. It was confirmed that patients carriers of high grade malinancy non-Hodgkin' s lymphoma, had the great percentage of neurologic complications (28,7 %), and average time between diagnosis of lymphoma and that of neurologic complications was shorter in these patients was (5,5 months). Survival after diagnosis of neurologic manifestations in most patients was under l year. In 14 patients deceaced, neurologic complication was main direct cause of death

Keywords : LYMPHOMA, NON-HODGKIN; LYMPHOMA [complications]; HODGKIN DISEASE; NEUROLOGIC MANIFESTATIONS; HEMIC AND LYMPHATIC DISEASES.

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