Abstract

CUBERO REGO, David; CUBERO MENENDEZ, Osiris; CABRERA MEHN, Mylene  and  ALVAREZ SANTANA, Reinaldo. Dementia with lewy bodies: A case report. Rev cubana med [online]. 2004, vol.43, n.5-6, pp. 0-0. ISSN 1561-302X.

It has been stated that dementia is the fourth basic cause of death in first world countries. Dementia with Lewy bodies (DLB) is the second cause of dementia in current necropsic studies, only surpassed by Alzheimer's disease. The first Cuban case of dementia with Lewy bodies was reported. A female white patient aged 89 with clinical diagnosis of dementia that died after 5 years of progressive deterioration. In the neuropathological study, the presence of Lewy bodies at the level of the black matter, locus ceruleus and transentorhinal cortex was evidenced by using the haematoxylin/eosin technique. The neurofibrillar pathology assessed by Bielschowsky technique corresponded to II stage Braak. A focal espongiform change was identified at the hippocampal level. The diagnosis of LBD variety with predominance of the brain stem was made. Literature and the main differential diagnoses were reviewed.

Keywords : Dementia; Lewy bodies.