Abstract

HANO GARCIA, Olga Marina; WOOD RODRIGUEZ, Lisette; GALBAN GARCIA, Enrique  and  ABREU VAZQUEZ, María del Rosario. Risk factors for colorectal cancer. Rev cubana med [online]. 2011, vol.50, n.2, pp. 118-132. ISSN 1561-302X.

The colorectal carcinoma (CLC) is one of the more frequent neoplasia in our practice, in past years there was a significant advance in the knowledge of mechanisms implicated in its development and progression. Such advance embraces from the identification of different genetic factors or molecular involved in its genesis. A case-control study was conducted on the CLC risk factors in adult patients (92 cases and 184 controls), diagnosed in the Institute of Gastroenterology. A survey was applied to collect these possible factors and to determine its relation to CLC. Analysis of these results showed that the risk factors with a great solid causality are: smoking, hip-waist index, vegetable consumption, physical inactivity and personal pathologic backgrounds of polyps and of other malignant tumors. There was predominance to left colon (descending, sigmoid and rectum) in both sexes. There was also predominance of the ulcerated type in both sexes, and the more frequent histological type was the adenocarcinoma.

Keywords : Colon; cancer; risk factors; vegetal fiber; polyps, hip-waist index.

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