Abstract

ALVAREZ GONZALEZ, Yanet; MAGRANS BUCH, Charles; MARMOL SONORA, Alexánder  and  GUTIERREZ GARCIA, Francisco. Pre-and post-dialysis renal transplant. Rev cubana med [online]. 2011, vol.50, n.2, pp. 133-139. ISSN 1561-302X.

Introduction: Renal transplantation is the therapeutic modality offering a great quality of life and survival for patients presenting with stage 5 chronic renal disease in, each day there a great trend to perform the renal transplantation in a patient without dialysis treatment. Objective: To compare the results obtained with the pre- and post- dialysis transplantation. Methods: A comparative study was conducted between the transplantation from deceased person performed in pre-dialysis time (23 patients) and that performed when patient with more than a year of dialysis treatment (82 patients) in the Institute of Nephrology during 1991-2001 and a follow-up until 2008. Thus, we compared a series of demographic and clinical features in both groups using a homogeneity test, Wilcoxon test for statistic analysis and the Kapplan Meier and Log-Rank test for survival analysis. Results: The differences present in both groups as regards the main features were not statistic significant. The frequency of the acute tubular necrosis and the acute rejection was great in the post-dialysis group, the graft and patient survival was better in pre-dialysis group, the differences founded were significant with p < 0,05. Conclusions: Patients of the pre-dialysis group had a better evolution.

Keywords : Chronic renal disease; renal transplantation; acute tubular necrosis; acute rejection.

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