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Revista Cubana de Medicina
On-line version ISSN 1561-302X
Abstract
ROIZ BALAGUER, Máximo Martín and MORALES BARRABIA, Ileana. Statins in the Primary, Secondary and Tertiary Prevention of Ischemic Stroke. Rev. Cuban de Med [online]. 2023, vol.62, n.4 Epub Dec 01, 2023. ISSN 1561-302X.
Introduction:
Ischemic stroke represents the third cause of mortality worldwide and the first cause of disability.
Objective:
To describe the beneficial effects of the prescription of statins in the primary, secondary and tertiary prevention of ischemic stroke.
Methods:
A bibliographic review on the prescription of statins in the primary, secondary and tertiary prevention of ischemic stroke was carried out. More than 400 articles published in MEDLINE/PubMed and Cochrane were reviewed. Only 50 articles met the selection criteria, which were published from May 2021 to June 2022.
Conclusions:
The use of statins decreases mortality in primary and secondary prevention. If they are used early in the acute phase (tertiary prevention), the infarcted area decreases, there is clinical improvement and acute phase reactants such as C-reactive protein decrease.
Keywords : statins; primary prevention; secondary and tertiary; ischemic stroke; complications, mortality.