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Revista Cubana de Medicina

On-line version ISSN 1561-302X

Abstract

RODRIGUEZ BLANCO, Suilbert; HENRIQUEZ ITALIN, Orlando; AGUILAR MEDINA, José  and  HERNANDEZ VALDES, Enmanuel. Neutrophils in the Diagnosis of Type 4 Myocardial Infarction. Rev. Cuban de Med [online]. 2024, vol.63  Epub Jan 29, 2024. ISSN 1561-302X.

Introduction:

Type 4 myocardial infarction is a complication of percutaneous coronary intervention that increases the inflammatory state of patients.

Objective:

To evaluate the diagnostic value of the absolute neutrophil count in the occurrence of type 4 myocardial infarction.

Methods:

A prospective cohort was carried out at Hermanos Ameijeiras Clinical Surgical Hospital. The universe consisted of 412 patients who underwent percutaneous coronary intervention from November 2018 to January 2021, two hundred thirty-two (232) patients form the sample. Clinical, anatomical and inflammatory variables were defined.

Results:

There were significant differences between patients with type 4 infarction and those who did not have this complication according to the clinical variables such as age, body mass index, diabetes mellitus, chronic kidney disease and ventricular systolic dysfunction. The subsequent elevation of the absolute neutrophil count when proceeding with an area under the 0.947 curve had good ability to discriminate this complication (p = 0.000). In the diagnosis of periprocedural infarction, the absolute neutrophil count was ≥ 7.35 after the procedure, it had 91.3% sensitivity and 96.2% specificity.

Conclusions:

Neutrophils were sensitive and specific for the diagnosis of type 4 myocardial infarction.

Keywords : neutrophils; periprocedural infarction of coronary intervention.

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