Abstract

DIAZ RIGAU, Leonor et al. Serogroups and antimicrobial susceptibility in Shigella strains. Rev Cubana Pediatr [online]. 2009, vol.81, n.1, pp. 0-0. ISSN 1561-3119.

INTRODUCTION: Shigella ssp. is one of the more important causal agents of acute diarrhea in children. Present research has as aim to know serogroups frequency and antimicrobial susceptibility to choice drugs, and to its alternatives. METHODS: A descriptive retrospective study was carried out between January 2004 and December 2006 of 34 strains of Shigella isolated from children lower than 5 years admitted in "Aleida Fernández Chardiet" Hospital in Güines Municipality by acute diarrheic disease. RESULTS: Serogroups included S. sonnei (70,5%), and S. flexeneri (29,5%). Both serogroups showed high levels of resistance to Trimethoprim-Sulfamethoxaxole and to Ampicillin and to in strains of S. sonnei there was resistance to nalidixic acid, and in that of S. flexeneri, to Chloramphenicol. All strains showed high percentages of sensibility to Cephtriaxone, Norphloxacine, and to Cyprophloxacine. The 70% of strains of S. sonnei were multi-resistant. Multiresistance pattern (Ampicillin, Trimetroprim-Sulfamethoxaxole and nalidixic acid) was present in both serogroups. CONCLUSIONS: Assessment and surveillance of resistance patterns allow control of policy on use of antibiotics in study region, and to foresee rise of strains resistant to new generation-drugs.

Keywords : Shigella ssp; acute diarrheic disease; antimicrobial susceptibility; serogroups; multiresistance patterns.

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