Abstract

VALDES ALONSO, María del Carmen et al. Some biochemical variables analyzed in obese adolescents with history of low birthweight. Rev Cubana Pediatr [online]. 2013, vol.85, n.4, pp. 439-447. ISSN 0034-7531.

Introduction: intrauterine malnutrition has been considered as being related to embrionary development problems that determine further occurrence of obesity, diabetes mellitus type 2, dyslipidemias, mitochondrial dysfunction and atherosclerosis.Objective: to determine the metabolic complications in obese adolescents with history of low birthweight.Methods: cross-sectional descriptive study of 50 obese patients of both sexes and aged 9 to 17 years and with a history of low birthweight. They had all been attended to in the outpatient endocrinology service of "Juan Manuel Marquez" teaching pediatric hospital from January 2011 to January 2012. Cholesterol, triglyceride, hepatic aminotransferase, glycemia and insulinemia on fasting and postprandially after 2 hours were estimated. Results: the studied biochemical variables did not show differences among the cutoffs used to classify birthweight. Piruvic gluthamic transaminase showed higher values in 15-17 years-old adolescents.Conclusions: hypertriglyceridemia was more elevated in females whereas hyperglycemia and hyperinsulinemia were elevated in males.

Keywords : insulin resistance; hyperinsulinism; non-alcoholic fatty liver.

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