Abstract

WANG, Ying et al. Appropriate indicated use for IVIG in neonatal infections. Rev Cubana Pediatr [online]. 2017, vol.89, n.1, pp. 92-97. ISSN 1561-3119.

Infection is a leading cause of mortality and morbidity in the newborn and preterm neonates due to immuno-incompetence in these patients. Administration of intravenous immunoglobulin (IVIG) provides immunoglobulin G (IgG) that can protect the body from infection. In theory, morbidity and mortality due to infections in newborns and preterm infants could be reduced by the administration of IVIG. Two meta-analyses were evaluated comparing IVIG to treat various infection versus conventional treatments. The results showed that IVIG is not effective as an adjunctive treatment for suspected or proven infections in neonates.

Keywords : intravenous immunoglobulin; newborn; preterm neonates; infection; meta-analyses.

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