Abstract

CARAVIA BERNALDO, Frank et al. Neonatal morbidity and birth weight in gestational diabetes patients under preventive insulin-treatment. Rev Cubana Obstet Ginecol [online]. 2010, vol.36, n.1, pp. 16-24. ISSN 1561-3062.

OBJECTIVE: To report the neonatal morbidity and the newborn weight in diabetes mellitus pregnants (DMP) under preventive or not insulin-treatment, carriers of risk factors for late hyperglycemias. METHODS: A total of 230 DMPs were studied during 2004-2008, who were divided into two groups, in one we administered Nordisk Novo human regular insulin at 0.3 Ud/kg dose of ideal weight, divided into 3 preprandial doses according to Valdés and Márquez method plus a estimated diet (intervention group) and in the other group (control group) only a estimated diet was administered, in no two groups less than 1 800 kcal/day. Chi² test and t Student test were used for results analysis with a value of p < 0.05. RESULTS: The neonatal morbidity concerning the neonatal hyperbilirubinemia and hypoglycemia had a frequency of 5.2 and 2.6 % for intervention group with a increase of 10,.4 and 6.1, respectively in control group. Frequency of neonatal body weight gain was of 6.1 % for intervention group and of 25.2 % for the treatment group only with a estimated diet, newborn frequency above 4.200 g was of 3.5 % in preventive insulin group increasing significantly to 11.3 % in control group with only the estimated diet. CONCLUSIONS: Preventive insulin treatment in diabetic pregnants with risk factors for a later hyperglycemia, achieve a significant reduction in body weight excess and in neonatal macrosomia according to our results, very probable by achieved anticipation to late hyperglycemia

Keywords : Diabetes Mellitus gestational; preventive insulin treatment.

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