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Revista Cubana de Medicina Militar
On-line version ISSN 1561-3046
Abstract
MIRANDA GOMEZ, Osvaldo et al. Clinical prognostic factors determining the survival of patients with the Ebola virus. Rev Cub Med Mil [online]. 2020, vol.49, n.4 Epub Dec 01, 2020. ISSN 1561-3046.
Introduction:
Ebola virus disease has a high lethality, which is why it is of great interest to carry out research that addresses clinical manifestations that could be prognostic factors for survival.
Objective:
To evaluate prognostic factors of Ebola patients.
Methods:
the universe was constituted by the totality (n = 350) of admitted patients. Summary measures were used for qualitative variables, point and interval estimates for quantitative variables, as well as Kaplan-Meier significance tests, Cox regression and Odds Ratio. We worked with a 95% level of reliability.
Results:
The overall survival was 42.5%. The average survival, approximately 10 days (CI: 9-11 days). Patients who were admitted in serious condition (OR = 3.76), who had low back pain (OR = 2.24), who reported headache (OR = 2.22), who presented fever (OR = 2.16), who they suffered from abdominal pain (OR = 1.95) and who were found to have conjunctival injection (OR = 1.86), were more likely to die than those who entered without these symptoms and signs.
Conclusions:
Survival was high, despite the complications presented. The symptoms and predictive signs of death in the patients were: the severity of the patient at admission, the presence of low back pain, headache, fever, abdominal pain and conjunctival injection.
Keywords : ebolavirus; hemorragic fever, ebola; lethality; ebolavirus, disease.