Abstract

MIRALLES ALONSO, Fernando et al. Behaviour of HIV/AIDS-related lymphoma in “Pedro Kourí” Institute. 2004-2005. Rev Cubana Med Trop [online]. 2006, vol.58, n.3, pp. 0-0. ISSN 1561-3054.

A prospective and descriptive study of 20 patients infected with HIV and admitted to “Pedro Kourí” Institute of Tropical Disease after a diagnosis of lymphoma was conducted. They were all evaluated at the onset of diagnosis by a thorough medical record exam and supportive studies such as complete blood count, globular sedimentation speed, CD4+ count, lactic acid dehydrogenase, HIV viral load, cytology and biopsy. Of this number, 85% presented with CD4+ count under 350 cell/mm³ at the time of diagnosis; however, only 55% showed viral loads exceeding 50 000 copies/mL. The predominant histological subtype was large diffuse cells and the most frequent location was the extrapulmonary site in 70% of cases. It called our attention that high levels of lactic acid dehydrogenase and extrapulmonary location of tumors were related. Statistically significant association was found  (p<0.05) between immunosuppresion condition of the patients given by CD4+ count below 350 cell/mm³ and advanced staging of the tumoral disease (stages III and IV).

Keywords : HIV/AIDS-related lymphoma; CD4+.

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