Abstract

MESA CUERVO, José René et al. Hodgkin´s disease: new clinico-pathologic features  . Rev Cubana Hematol Inmunol Hemoter [online]. 2000, vol.16, n.1, pp. 21-29. ISSN 1561-2996.

Hodgkin´s disease, considered a lymphoid neoplasia, is classified in 5 groups, since Rye Conference in 1960. Nodular sclerosis variety is commonest, generally involve supradiaphragmatic regions and is divided in two grades with distinct morphologic ant prognostic features. Grade II of badly prognosis demand a more aggresive treatment. Mixed cellularity ussualy has a greater disease spreading level and joined with nodular sclerosis, are classified as classic forms of disease, positive to immunophenotypical markers, CD15 and CD30. Lymphocytic predominance is to be considered as a cell lymphoma of germinal center and emerge as a distinct clinico-pathologic entity with a unfavourable prognosis. Differential diagnosis in non-Hodgkin´s lymphomas, unusually is possible and at present, delimitation between both types of lymphoma, es not well defined. Non classified group have a tendency to disappear

Keywords : HODGKIN DISEASES; LYMPHOCYTE DEPLETION; LYMPHOMA, NON HODGKIN [pathology].

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