Abstract

ALFONSO VALDES, María Elena et al. Alloantibodies against blood cells in nuliparous pregnant women before and after induced abortions. Rev Cubana Hematol Inmunol Hemoter [online]. 2008, vol.24, n.2, pp. 0-0. ISSN 1561-2996.

A prospective study was undertaken to know the prevalence of alloimmunization against blood cells in 80 young nuliparous females with neither history of blood transfussion nor miscarriages that were subjected to induced abortion before the 12 weeks of gestation. The presence of alloantibodies against erythrocytary, leukocitary and platelet antigens was determined before and 6 months after abortion. No erythrocytary antibodies were detected in any of the cases. Antibodies against leukocytes and/or platelets were found in 30 % of the cases in the initial study, and in 38.75 % 6 months after abortion. On characterizing the antibodies of the initial sample, it was observed that 79.16 % were anti-HLA and 20.83 % were granulocyte-specific. In the final sample, 38.70 % were anti-HLA, 54.83 % granulocyte-specific and 6.45 % platelet-specific. No relation was found between the number of pregnancies and the presence of alloantibodies.

Keywords : alloimmnuzation; antibodies; abortion; pregnancy; HLA; antiplatelet; antigranulocyte.

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